SNORD115-22

Summary

SNORD115-22 (small nucleolar RNA, C/D box 115-22, HGNC:33041) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033799 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33041
Approved symbol	SNORD115-22
Name	small nucleolar RNA, C/D box 115-22
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-52-22
Ensembl gene	ENSG00000201326
Ensembl biotype	snoRNA
Entrez	100033799
RNAcentral	URS000008F76B — snoRNA, 82 nt, 3 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364456

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364456 — 1 exons

Exon	Start	End
ENSE00001808424	25209918	25209999

Expression profiles

Bgee: expression breadth broad, 72 present calls, max score 86.69.

Top tissues by expression

72 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	86.69	gold quality
adrenal tissue	UBERON:0018303	77.37	gold quality
liver	UBERON:0002107	74.49	gold quality
kidney	UBERON:0002113	72.28	gold quality
Brodmann (1909) area 9	UBERON:0013540	71.98	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.65	gold quality
blood	UBERON:0000178	70.58	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	68.16	gold quality
hypothalamus	UBERON:0001898	67.75	gold quality
skin of abdomen	UBERON:0001416	66.97	gold quality
right lobe of liver	UBERON:0001114	66.95	gold quality
prefrontal cortex	UBERON:0000451	66.57	gold quality
anterior cingulate cortex	UBERON:0009835	65.92	gold quality
gastrocnemius	UBERON:0001388	65.78	gold quality
right coronary artery	UBERON:0001625	65.71	gold quality
substantia nigra	UBERON:0002038	65.17	gold quality
Ammon’s horn	UBERON:0001954	64.84	gold quality
cerebellar hemisphere	UBERON:0002245	64.68	gold quality
right adrenal gland	UBERON:0001233	64.59	gold quality
brain	UBERON:0000955	64.52	gold quality
islet of Langerhans	UBERON:0000006	64.51	gold quality
amygdala	UBERON:0001876	63.64	gold quality
myometrium	UBERON:0001296	63.51	gold quality
omental fat pad	UBERON:0010414	63.45	gold quality
corpus callosum	UBERON:0002336	63.24	gold quality
putamen	UBERON:0001874	62.97	gold quality
caudate nucleus	UBERON:0001873	62.90	gold quality
right hemisphere of cerebellum	UBERON:0014890	62.84	gold quality
multicellular organism	UBERON:0000468	62.49	gold quality
frontal cortex	UBERON:0001870	62.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (49): SNORD115-34 (ENSG00000199311), SNORD115-12 (ENSG00000199453), SNORD115-25 (ENSG00000199489), SNORD115-29 (ENSG00000199704), SNORD115-2 (ENSG00000199712), SNORD115-9 (ENSG00000199782), SNORD115-21 (ENSG00000199833), SNORD115-14 (ENSG00000199960), SNORD115-19 (ENSG00000199968), SNORD115-3 (ENSG00000199970), SNORD115-18 (ENSG00000200163), SNORD115-24 (ENSG00000200398), SNORD115-41 (ENSG00000200478), SNORD115-11 (ENSG00000200486), SNORD115-5 (ENSG00000200503), SNORD115-39 (ENSG00000200564), SNORD115-33 (ENSG00000200593), SNORD115-37 (ENSG00000200638), SNORD115-4 (ENSG00000200680), SNORD115-8 (ENSG00000200726), SNORD115-16 (ENSG00000200757), SNORD115-28 (ENSG00000200801), SNORD115-6 (ENSG00000200812), SNORD115-32 (ENSG00000200949), SNORD115-30 (ENSG00000200987), SNORD115-42 (ENSG00000201143), SNORD115-27 (ENSG00000201300), SNORD115-23 (ENSG00000201331), SNORD115-17 (ENSG00000201482), SNORD115-48 (ENSG00000201634), SNORD115-15 (ENSG00000201679), SNORD115-1 (ENSG00000201831), SNORD115-38 (ENSG00000201907), SNORD115-10 (ENSG00000201943), SNORD115-20 (ENSG00000201969), SNORD115-35 (ENSG00000201992), SNORD115-31 (ENSG00000202188), SNORD115-44 (ENSG00000202261), SNORD115-43 (ENSG00000202373), SNORD115-36 (ENSG00000202499)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.