SNORD115-23

Summary

SNORD115-23 (small nucleolar RNA, C/D box 115-23, HGNC:33042) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033800 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33042
Approved symbol	SNORD115-23
Name	small nucleolar RNA, C/D box 115-23
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-52-23
Ensembl gene	ENSG00000201331
Ensembl biotype	snoRNA
Entrez	100033800
RNAcentral	URS0000294E00 — snoRNA, 82 nt, 10 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364461

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364461 — 1 exons

Exon	Start	End
ENSE00001439224	25211796	25211877

Expression profiles

Bgee: expression breadth broad, 49 present calls, max score 96.25.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0746 / max 14.3536, expressed in 35 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
145547	0.0746	35

Top tissues by expression

49 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	96.25	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.46	gold quality
liver	UBERON:0002107	84.90	gold quality
adult mammalian kidney	UBERON:0000082	80.27	gold quality
heart	UBERON:0000948	79.42	gold quality
Brodmann (1909) area 9	UBERON:0013540	79.09	gold quality
adrenal tissue	UBERON:0018303	78.85	gold quality
heart left ventricle	UBERON:0002084	75.64	gold quality
monocyte	CL:0000576	74.10	gold quality
gastrocnemius	UBERON:0001388	74.07	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	73.37	gold quality
prefrontal cortex	UBERON:0000451	73.10	gold quality
lung	UBERON:0002048	72.83	gold quality
blood	UBERON:0000178	71.61	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	70.72	gold quality
body of pancreas	UBERON:0001150	69.14	gold quality
small intestine Peyer’s patch	UBERON:0003454	68.13	gold quality
Ammon’s horn	UBERON:0001954	67.94	gold quality
left adrenal gland cortex	UBERON:0035825	67.45	gold quality
anterior cingulate cortex	UBERON:0009835	66.67	gold quality
muscle layer of sigmoid colon	UBERON:0035805	66.58	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	66.46	gold quality
esophagus mucosa	UBERON:0002469	66.38	gold quality
transverse colon	UBERON:0001157	66.28	gold quality
lower esophagus muscularis layer	UBERON:0035833	65.58	gold quality
brain	UBERON:0000955	65.30	gold quality
caudate nucleus	UBERON:0001873	65.24	gold quality
ascending aorta	UBERON:0001496	64.70	gold quality
substantia nigra	UBERON:0002038	64.63	gold quality
nucleus accumbens	UBERON:0001882	64.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.17

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (49): SNORD115-34 (ENSG00000199311), SNORD115-12 (ENSG00000199453), SNORD115-25 (ENSG00000199489), SNORD115-29 (ENSG00000199704), SNORD115-2 (ENSG00000199712), SNORD115-9 (ENSG00000199782), SNORD115-21 (ENSG00000199833), SNORD115-14 (ENSG00000199960), SNORD115-19 (ENSG00000199968), SNORD115-3 (ENSG00000199970), SNORD115-18 (ENSG00000200163), SNORD115-24 (ENSG00000200398), SNORD115-41 (ENSG00000200478), SNORD115-11 (ENSG00000200486), SNORD115-5 (ENSG00000200503), SNORD115-39 (ENSG00000200564), SNORD115-33 (ENSG00000200593), SNORD115-37 (ENSG00000200638), SNORD115-4 (ENSG00000200680), SNORD115-8 (ENSG00000200726), SNORD115-16 (ENSG00000200757), SNORD115-28 (ENSG00000200801), SNORD115-6 (ENSG00000200812), SNORD115-32 (ENSG00000200949), SNORD115-30 (ENSG00000200987), SNORD115-42 (ENSG00000201143), SNORD115-27 (ENSG00000201300), SNORD115-22 (ENSG00000201326), SNORD115-17 (ENSG00000201482), SNORD115-48 (ENSG00000201634), SNORD115-15 (ENSG00000201679), SNORD115-1 (ENSG00000201831), SNORD115-38 (ENSG00000201907), SNORD115-10 (ENSG00000201943), SNORD115-20 (ENSG00000201969), SNORD115-35 (ENSG00000201992), SNORD115-31 (ENSG00000202188), SNORD115-44 (ENSG00000202261), SNORD115-43 (ENSG00000202373), SNORD115-36 (ENSG00000202499)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.