SNORD115-27

Summary

SNORD115-27 (small nucleolar RNA, C/D box 115-27, HGNC:33046) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100036564 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33046
Approved symbol	SNORD115-27
Name	small nucleolar RNA, C/D box 115-27
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-52-27
Ensembl gene	ENSG00000201300
Ensembl biotype	snoRNA
Entrez	100036564
RNAcentral	URS00003E4134 — snoRNA, 76 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364430

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364430 — 1 exons

Exon	Start	End
ENSE00001808043	25220497	25220578

Expression profiles

Bgee: expression breadth broad, 39 present calls, max score 77.40.

Top tissues by expression

39 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	77.40	gold quality
heart	UBERON:0000948	76.22	gold quality
monocyte	CL:0000576	70.36	gold quality
blood	UBERON:0000178	70.08	gold quality
stomach	UBERON:0000945	69.18	gold quality
substantia nigra	UBERON:0002038	68.51	gold quality
prefrontal cortex	UBERON:0000451	68.47	gold quality
body of pancreas	UBERON:0001150	68.44	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	68.20	gold quality
urinary bladder	UBERON:0001255	66.75	gold quality
gall bladder	UBERON:0002110	66.10	gold quality
anterior cingulate cortex	UBERON:0009835	66.01	gold quality
corpus callosum	UBERON:0002336	65.88	gold quality
nucleus accumbens	UBERON:0001882	65.84	gold quality
ascending aorta	UBERON:0001496	65.36	gold quality
body of stomach	UBERON:0001161	65.31	gold quality
transverse colon	UBERON:0001157	64.96	gold quality
putamen	UBERON:0001874	64.72	gold quality
brain	UBERON:0000955	64.66	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.38	gold quality
multicellular organism	UBERON:0000468	64.25	gold quality
right frontal lobe	UBERON:0002810	63.79	gold quality
Ammon’s horn	UBERON:0001954	63.58	gold quality
esophagus mucosa	UBERON:0002469	63.53	gold quality
hypothalamus	UBERON:0001898	63.39	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.30	gold quality
caudate nucleus	UBERON:0001873	63.19	gold quality
cerebellar hemisphere	UBERON:0002245	63.05	gold quality
right hemisphere of cerebellum	UBERON:0014890	63.01	gold quality
amygdala	UBERON:0001876	62.43	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.17

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (49): SNORD115-34 (ENSG00000199311), SNORD115-12 (ENSG00000199453), SNORD115-25 (ENSG00000199489), SNORD115-29 (ENSG00000199704), SNORD115-2 (ENSG00000199712), SNORD115-9 (ENSG00000199782), SNORD115-21 (ENSG00000199833), SNORD115-14 (ENSG00000199960), SNORD115-19 (ENSG00000199968), SNORD115-3 (ENSG00000199970), SNORD115-18 (ENSG00000200163), SNORD115-24 (ENSG00000200398), SNORD115-41 (ENSG00000200478), SNORD115-11 (ENSG00000200486), SNORD115-5 (ENSG00000200503), SNORD115-39 (ENSG00000200564), SNORD115-33 (ENSG00000200593), SNORD115-37 (ENSG00000200638), SNORD115-4 (ENSG00000200680), SNORD115-8 (ENSG00000200726), SNORD115-16 (ENSG00000200757), SNORD115-28 (ENSG00000200801), SNORD115-6 (ENSG00000200812), SNORD115-32 (ENSG00000200949), SNORD115-30 (ENSG00000200987), SNORD115-42 (ENSG00000201143), SNORD115-22 (ENSG00000201326), SNORD115-23 (ENSG00000201331), SNORD115-17 (ENSG00000201482), SNORD115-48 (ENSG00000201634), SNORD115-15 (ENSG00000201679), SNORD115-1 (ENSG00000201831), SNORD115-38 (ENSG00000201907), SNORD115-10 (ENSG00000201943), SNORD115-20 (ENSG00000201969), SNORD115-35 (ENSG00000201992), SNORD115-31 (ENSG00000202188), SNORD115-44 (ENSG00000202261), SNORD115-43 (ENSG00000202373), SNORD115-36 (ENSG00000202499)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.