SNORD115-34

Summary

SNORD115-34 (small nucleolar RNA, C/D box 115-34, HGNC:33053) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033808 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33053
Approved symbol	SNORD115-34
Name	small nucleolar RNA, C/D box 115-34
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-52-34
Ensembl gene	ENSG00000199311
Ensembl biotype	snoRNA
Entrez	100033808
RNAcentral	URS000035BEB3 — snoRNA, 82 nt, 15 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000362441

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000362441 — 1 exons

Exon	Start	End
ENSE00001807604	25232387	25232468

Expression profiles

Bgee: expression breadth broad, 36 present calls, max score 95.84.

Top tissues by expression

36 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	95.84	gold quality
liver	UBERON:0002107	86.36	gold quality
adrenal tissue	UBERON:0018303	82.28	gold quality
Brodmann (1909) area 9	UBERON:0013540	79.12	gold quality
blood	UBERON:0000178	78.28	gold quality
monocyte	CL:0000576	77.66	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	74.51	gold quality
lung	UBERON:0002048	73.44	gold quality
left adrenal gland cortex	UBERON:0035825	72.97	gold quality
adult mammalian kidney	UBERON:0000082	72.79	gold quality
ascending aorta	UBERON:0001496	68.21	gold quality
right lobe of liver	UBERON:0001114	67.21	gold quality
putamen	UBERON:0001874	67.15	gold quality
heart	UBERON:0000948	66.38	gold quality
esophagus mucosa	UBERON:0002469	66.18	gold quality
transverse colon	UBERON:0001157	66.15	gold quality
substantia nigra	UBERON:0002038	65.34	gold quality
amygdala	UBERON:0001876	65.25	gold quality
frontal cortex	UBERON:0001870	65.01	gold quality
nucleus accumbens	UBERON:0001882	64.23	gold quality
Ammon’s horn	UBERON:0001954	63.95	gold quality
gastrocnemius	UBERON:0001388	63.88	gold quality
caudate nucleus	UBERON:0001873	62.54	gold quality
thoracic mammary gland	UBERON:0005200	62.51	gold quality
minor salivary gland	UBERON:0001830	62.37	gold quality
right frontal lobe	UBERON:0002810	61.71	gold quality
right hemisphere of cerebellum	UBERON:0014890	61.36	gold quality
cerebellar hemisphere	UBERON:0002245	60.61	gold quality
lower esophagus muscularis layer	UBERON:0035833	60.25	gold quality
anterior cingulate cortex	UBERON:0009835	60.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (49): SNORD115-12 (ENSG00000199453), SNORD115-25 (ENSG00000199489), SNORD115-29 (ENSG00000199704), SNORD115-2 (ENSG00000199712), SNORD115-9 (ENSG00000199782), SNORD115-21 (ENSG00000199833), SNORD115-14 (ENSG00000199960), SNORD115-19 (ENSG00000199968), SNORD115-3 (ENSG00000199970), SNORD115-18 (ENSG00000200163), SNORD115-24 (ENSG00000200398), SNORD115-41 (ENSG00000200478), SNORD115-11 (ENSG00000200486), SNORD115-5 (ENSG00000200503), SNORD115-39 (ENSG00000200564), SNORD115-33 (ENSG00000200593), SNORD115-37 (ENSG00000200638), SNORD115-4 (ENSG00000200680), SNORD115-8 (ENSG00000200726), SNORD115-16 (ENSG00000200757), SNORD115-28 (ENSG00000200801), SNORD115-6 (ENSG00000200812), SNORD115-32 (ENSG00000200949), SNORD115-30 (ENSG00000200987), SNORD115-42 (ENSG00000201143), SNORD115-27 (ENSG00000201300), SNORD115-22 (ENSG00000201326), SNORD115-23 (ENSG00000201331), SNORD115-17 (ENSG00000201482), SNORD115-48 (ENSG00000201634), SNORD115-15 (ENSG00000201679), SNORD115-1 (ENSG00000201831), SNORD115-38 (ENSG00000201907), SNORD115-10 (ENSG00000201943), SNORD115-20 (ENSG00000201969), SNORD115-35 (ENSG00000201992), SNORD115-31 (ENSG00000202188), SNORD115-44 (ENSG00000202261), SNORD115-43 (ENSG00000202373), SNORD115-36 (ENSG00000202499)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.