SNORD115-4

gene
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Also known as HBII-52-4

Summary

SNORD115-4 (small nucleolar RNA, C/D box 115-4, HGNC:33023) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033441 — RefSeq curated summary.

At a glance

  • Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

FieldValue
HGNC IDHGNC:33023
Approved symbolSNORD115-4
Namesmall nucleolar RNA, C/D box 115-4
Location15q11.2
Locus typeRNA, small nucleolar
StatusApproved
AliasesHBII-52-4
Ensembl geneENSG00000200680
Ensembl biotypesnoRNA
Entrez100033441
RNAcentralURS00004F749B — snoRNA, 82 nt, 13 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000363810

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000363810 — 1 exons

ExonStartEnd
ENSE000018069772517683225176913

Expression profiles

Bgee: expression breadth broad, 53 present calls, max score 81.84.

Top tissues by expression

53 total, by Bgee expression score (0-100, higher = more expressed):

TissueAnatomy IDExpression scoreQuality
adult mammalian kidneyUBERON:000008281.84gold quality
skin of legUBERON:000151177.41gold quality
liverUBERON:000210776.66gold quality
tibial arteryUBERON:000761074.39gold quality
prefrontal cortexUBERON:000045174.17gold quality
right hemisphere of cerebellumUBERON:001489071.75gold quality
right lobe of liverUBERON:000111471.50gold quality
bloodUBERON:000017870.73gold quality
Brodmann (1909) area 9UBERON:001354070.19gold quality
cerebellar hemisphereUBERON:000224570.14gold quality
heart left ventricleUBERON:000208470.11gold quality
lower esophagus muscularis layerUBERON:003583370.05gold quality
dorsolateral prefrontal cortexUBERON:000983469.69gold quality
body of pancreasUBERON:000115069.62gold quality
hypothalamusUBERON:000189868.92gold quality
putamenUBERON:000187468.65gold quality
anterior cingulate cortexUBERON:000983567.95gold quality
gastrocnemiusUBERON:000138867.72gold quality
nucleus accumbensUBERON:000188267.70gold quality
caudate nucleusUBERON:000187367.38gold quality
Ammon’s hornUBERON:000195467.24gold quality
lungUBERON:000204867.10gold quality
thoracic aortaUBERON:000151566.98gold quality
substantia nigraUBERON:000203866.94gold quality
ascending aortaUBERON:000149666.87gold quality
amygdalaUBERON:000187666.75gold quality
frontal cortexUBERON:000187066.72gold quality
right frontal lobeUBERON:000281066.45gold quality
subcutaneous adipose tissueUBERON:000219065.68gold quality
C1 segment of cervical spinal cordUBERON:000646965.62gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

ExperimentMarker?Max mean expression
E-ANND-3no0.10

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (49): SNORD115-34 (ENSG00000199311), SNORD115-12 (ENSG00000199453), SNORD115-25 (ENSG00000199489), SNORD115-29 (ENSG00000199704), SNORD115-2 (ENSG00000199712), SNORD115-9 (ENSG00000199782), SNORD115-21 (ENSG00000199833), SNORD115-14 (ENSG00000199960), SNORD115-19 (ENSG00000199968), SNORD115-3 (ENSG00000199970), SNORD115-18 (ENSG00000200163), SNORD115-24 (ENSG00000200398), SNORD115-41 (ENSG00000200478), SNORD115-11 (ENSG00000200486), SNORD115-5 (ENSG00000200503), SNORD115-39 (ENSG00000200564), SNORD115-33 (ENSG00000200593), SNORD115-37 (ENSG00000200638), SNORD115-8 (ENSG00000200726), SNORD115-16 (ENSG00000200757), SNORD115-28 (ENSG00000200801), SNORD115-6 (ENSG00000200812), SNORD115-32 (ENSG00000200949), SNORD115-30 (ENSG00000200987), SNORD115-42 (ENSG00000201143), SNORD115-27 (ENSG00000201300), SNORD115-22 (ENSG00000201326), SNORD115-23 (ENSG00000201331), SNORD115-17 (ENSG00000201482), SNORD115-48 (ENSG00000201634), SNORD115-15 (ENSG00000201679), SNORD115-1 (ENSG00000201831), SNORD115-38 (ENSG00000201907), SNORD115-10 (ENSG00000201943), SNORD115-20 (ENSG00000201969), SNORD115-35 (ENSG00000201992), SNORD115-31 (ENSG00000202188), SNORD115-44 (ENSG00000202261), SNORD115-43 (ENSG00000202373), SNORD115-36 (ENSG00000202499)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.

  • Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): 15q11q13 microduplication syndrome