SNORD115-4
gene geneOn this page
Also known as HBII-52-4
Summary
SNORD115-4 (small nucleolar RNA, C/D box 115-4, HGNC:33023) is a small nucleolar RNA gene on chromosome 15q11.2.
Predicted to be involved in RNA processing. Predicted to be located in nucleolus.
Source: NCBI Gene 100033441 — RefSeq curated summary.
At a glance
- Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:33023 |
| Approved symbol | SNORD115-4 |
| Name | small nucleolar RNA, C/D box 115-4 |
| Location | 15q11.2 |
| Locus type | RNA, small nucleolar |
| Status | Approved |
| Aliases | HBII-52-4 |
| Ensembl gene | ENSG00000200680 |
| Ensembl biotype | snoRNA |
| Entrez | 100033441 |
| RNAcentral | URS00004F749B — snoRNA, 82 nt, 13 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 snoRNA
ENST00000363810
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000363810 — 1 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001806977 | 25176832 | 25176913 |
Expression profiles
Bgee: expression breadth broad, 53 present calls, max score 81.84.
Top tissues by expression
53 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| adult mammalian kidney | UBERON:0000082 | 81.84 | gold quality |
| skin of leg | UBERON:0001511 | 77.41 | gold quality |
| liver | UBERON:0002107 | 76.66 | gold quality |
| tibial artery | UBERON:0007610 | 74.39 | gold quality |
| prefrontal cortex | UBERON:0000451 | 74.17 | gold quality |
| right hemisphere of cerebellum | UBERON:0014890 | 71.75 | gold quality |
| right lobe of liver | UBERON:0001114 | 71.50 | gold quality |
| blood | UBERON:0000178 | 70.73 | gold quality |
| Brodmann (1909) area 9 | UBERON:0013540 | 70.19 | gold quality |
| cerebellar hemisphere | UBERON:0002245 | 70.14 | gold quality |
| heart left ventricle | UBERON:0002084 | 70.11 | gold quality |
| lower esophagus muscularis layer | UBERON:0035833 | 70.05 | gold quality |
| dorsolateral prefrontal cortex | UBERON:0009834 | 69.69 | gold quality |
| body of pancreas | UBERON:0001150 | 69.62 | gold quality |
| hypothalamus | UBERON:0001898 | 68.92 | gold quality |
| putamen | UBERON:0001874 | 68.65 | gold quality |
| anterior cingulate cortex | UBERON:0009835 | 67.95 | gold quality |
| gastrocnemius | UBERON:0001388 | 67.72 | gold quality |
| nucleus accumbens | UBERON:0001882 | 67.70 | gold quality |
| caudate nucleus | UBERON:0001873 | 67.38 | gold quality |
| Ammon’s horn | UBERON:0001954 | 67.24 | gold quality |
| lung | UBERON:0002048 | 67.10 | gold quality |
| thoracic aorta | UBERON:0001515 | 66.98 | gold quality |
| substantia nigra | UBERON:0002038 | 66.94 | gold quality |
| ascending aorta | UBERON:0001496 | 66.87 | gold quality |
| amygdala | UBERON:0001876 | 66.75 | gold quality |
| frontal cortex | UBERON:0001870 | 66.72 | gold quality |
| right frontal lobe | UBERON:0002810 | 66.45 | gold quality |
| subcutaneous adipose tissue | UBERON:0002190 | 65.68 | gold quality |
| C1 segment of cervical spinal cord | UBERON:0006469 | 65.62 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 0.10 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Paralogs (49): SNORD115-34 (ENSG00000199311), SNORD115-12 (ENSG00000199453), SNORD115-25 (ENSG00000199489), SNORD115-29 (ENSG00000199704), SNORD115-2 (ENSG00000199712), SNORD115-9 (ENSG00000199782), SNORD115-21 (ENSG00000199833), SNORD115-14 (ENSG00000199960), SNORD115-19 (ENSG00000199968), SNORD115-3 (ENSG00000199970), SNORD115-18 (ENSG00000200163), SNORD115-24 (ENSG00000200398), SNORD115-41 (ENSG00000200478), SNORD115-11 (ENSG00000200486), SNORD115-5 (ENSG00000200503), SNORD115-39 (ENSG00000200564), SNORD115-33 (ENSG00000200593), SNORD115-37 (ENSG00000200638), SNORD115-8 (ENSG00000200726), SNORD115-16 (ENSG00000200757), SNORD115-28 (ENSG00000200801), SNORD115-6 (ENSG00000200812), SNORD115-32 (ENSG00000200949), SNORD115-30 (ENSG00000200987), SNORD115-42 (ENSG00000201143), SNORD115-27 (ENSG00000201300), SNORD115-22 (ENSG00000201326), SNORD115-23 (ENSG00000201331), SNORD115-17 (ENSG00000201482), SNORD115-48 (ENSG00000201634), SNORD115-15 (ENSG00000201679), SNORD115-1 (ENSG00000201831), SNORD115-38 (ENSG00000201907), SNORD115-10 (ENSG00000201943), SNORD115-20 (ENSG00000201969), SNORD115-35 (ENSG00000201992), SNORD115-31 (ENSG00000202188), SNORD115-44 (ENSG00000202261), SNORD115-43 (ENSG00000202373), SNORD115-36 (ENSG00000202499)
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): 15q11q13 microduplication syndrome