SNORD116-12

Summary

SNORD116-12 (small nucleolar RNA, C/D box 116-12, HGNC:33078) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033424 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33078
Approved symbol	SNORD116-12
Name	small nucleolar RNA, C/D box 116-12
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-85-12
Ensembl gene	ENSG00000207197
Ensembl biotype	snoRNA
Entrez	100033424
RNAcentral	URS000075B1B4 — snoRNA, 94 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384468

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384468 — 1 exons

Exon	Start	End
ENSE00001808860	25077051	25077142

Expression profiles

Bgee: expression breadth broad, 44 present calls, max score 91.51.

Top tissues by expression

44 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	91.51	gold quality
skeletal muscle tissue	UBERON:0001134	83.30	gold quality
adrenal tissue	UBERON:0018303	72.34	gold quality
adult mammalian kidney	UBERON:0000082	71.81	gold quality
right atrium auricular region	UBERON:0006631	70.57	gold quality
body of stomach	UBERON:0001161	69.59	gold quality
muscle of leg	UBERON:0001383	69.18	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	68.74	gold quality
thoracic mammary gland	UBERON:0005200	68.32	gold quality
gastrocnemius	UBERON:0001388	68.24	gold quality
lung	UBERON:0002048	67.56	gold quality
lower esophagus muscularis layer	UBERON:0035833	66.59	gold quality
heart	UBERON:0000948	66.58	gold quality
islet of Langerhans	UBERON:0000006	66.31	gold quality
descending thoracic aorta	UBERON:0002345	65.51	gold quality
blood	UBERON:0000178	65.23	gold quality
putamen	UBERON:0001874	65.06	gold quality
esophagus mucosa	UBERON:0002469	64.37	gold quality
muscle layer of sigmoid colon	UBERON:0035805	64.35	gold quality
heart left ventricle	UBERON:0002084	64.32	gold quality
left coronary artery	UBERON:0001626	64.26	gold quality
left ovary	UBERON:0002119	64.09	gold quality
ascending aorta	UBERON:0001496	63.57	gold quality
subcutaneous adipose tissue	UBERON:0002190	62.61	gold quality
right lobe of thyroid gland	UBERON:0001119	62.30	gold quality
upper lobe of left lung	UBERON:0008952	62.26	gold quality
Ammon’s horn	UBERON:0001954	61.97	gold quality
tibial nerve	UBERON:0001323	61.81	gold quality
right frontal lobe	UBERON:0002810	61.03	gold quality
substantia nigra	UBERON:0002038	60.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.37

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (32): SNORD116-10 (ENSG00000200661), SNORD116 (ENSG00000202498), SNORD116-11 (ENSG00000206609), SNORD116-14 (ENSG00000206621), SNORD116-17 (ENSG00000206656), SNORD116-18 (ENSG00000206688), SNORD116-9 (ENSG00000206727), SNORD116-2 (ENSG00000207001), SNORD116-3 (ENSG00000207014), SNORD116-1 (ENSG00000207063), SNORD116-8 (ENSG00000207093), SNORD116-7 (ENSG00000207133), SNORD116-13 (ENSG00000207137), SNORD116-15 (ENSG00000207174), SNORD116-5 (ENSG00000207191), SNORD116-29 (ENSG00000207245), SNORD116-16 (ENSG00000207263), SNORD116-24 (ENSG00000207279), SNORD116-23 (ENSG00000207375), SNORD116-6 (ENSG00000207442), SNORD116-19 (ENSG00000207460), SNORD116 (ENSG00000212553), SNORD116-26 (ENSG00000251815), SNORD116-27 (ENSG00000251896), SNORD116-30 (ENSG00000252277), SNORD116-25 (ENSG00000252326), SNORD116 (ENSG00000252985), SNORD116-22 (ENSG00000275127), SNORD116-4 (ENSG00000275529), SNORD116-21 (ENSG00000277785), SNORD116-28 (ENSG00000278123), SNORD116-20 (ENSG00000278715)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.