SNORD116-19

Summary

SNORD116-19 (small nucleolar RNA, C/D box 116-19, HGNC:33085) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 727708 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33085
Approved symbol	SNORD116-19
Name	small nucleolar RNA, C/D box 116-19
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-85-19
Ensembl gene	ENSG00000207460
Ensembl biotype	snoRNA
Entrez	727708
RNAcentral	URS000075E0F0 — snoRNA, 94 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384729

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384729 — 1 exons

Exon	Start	End
ENSE00001808169	25086527	25086618

Expression profiles

Bgee: expression breadth broad, 59 present calls, max score 99.19.

Top tissues by expression

59 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.19	gold quality
adrenal tissue	UBERON:0018303	92.76	gold quality
liver	UBERON:0002107	85.10	gold quality
kidney	UBERON:0002113	82.65	gold quality
lung	UBERON:0002048	79.77	gold quality
stomach	UBERON:0000945	77.76	gold quality
heart	UBERON:0000948	74.95	gold quality
Brodmann (1909) area 9	UBERON:0013540	74.64	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	73.78	gold quality
blood	UBERON:0000178	73.23	gold quality
adult mammalian kidney	UBERON:0000082	71.70	gold quality
intestine	UBERON:0000160	69.04	gold quality
monocyte	CL:0000576	68.00	gold quality
fundus of stomach	UBERON:0001160	67.08	gold quality
endometrium	UBERON:0001295	66.00	gold quality
cerebral cortex	UBERON:0000956	65.65	gold quality
tibial nerve	UBERON:0001323	63.05	gold quality
skeletal muscle tissue	UBERON:0001134	62.04	gold quality
testis	UBERON:0000473	61.91	gold quality
prostate gland	UBERON:0002367	60.89	gold quality
islet of Langerhans	UBERON:0000006	60.34	gold quality
muscle of leg	UBERON:0001383	59.68	gold quality
small intestine	UBERON:0002108	59.62	gold quality
body of pancreas	UBERON:0001150	58.03	gold quality
pituitary gland	UBERON:0000007	57.89	gold quality
right atrium auricular region	UBERON:0006631	57.29	gold quality
anterior cingulate cortex	UBERON:0009835	57.17	gold quality
gastrocnemius	UBERON:0001388	56.54	gold quality
heart left ventricle	UBERON:0002084	56.27	gold quality
omental fat pad	UBERON:0010414	55.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.95

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• SNORD116-19, located in a cluster of imprinted genes on chromosome 15q11, is imprinted, with preferential expression from the paternal allele. (PMID:11726556)

Cross-species orthologs

0 orthologs

Paralogs (32): SNORD116-10 (ENSG00000200661), SNORD116 (ENSG00000202498), SNORD116-11 (ENSG00000206609), SNORD116-14 (ENSG00000206621), SNORD116-17 (ENSG00000206656), SNORD116-18 (ENSG00000206688), SNORD116-9 (ENSG00000206727), SNORD116-2 (ENSG00000207001), SNORD116-3 (ENSG00000207014), SNORD116-1 (ENSG00000207063), SNORD116-8 (ENSG00000207093), SNORD116-7 (ENSG00000207133), SNORD116-13 (ENSG00000207137), SNORD116-15 (ENSG00000207174), SNORD116-5 (ENSG00000207191), SNORD116-12 (ENSG00000207197), SNORD116-29 (ENSG00000207245), SNORD116-16 (ENSG00000207263), SNORD116-24 (ENSG00000207279), SNORD116-23 (ENSG00000207375), SNORD116-6 (ENSG00000207442), SNORD116 (ENSG00000212553), SNORD116-26 (ENSG00000251815), SNORD116-27 (ENSG00000251896), SNORD116-30 (ENSG00000252277), SNORD116-25 (ENSG00000252326), SNORD116 (ENSG00000252985), SNORD116-22 (ENSG00000275127), SNORD116-4 (ENSG00000275529), SNORD116-21 (ENSG00000277785), SNORD116-28 (ENSG00000278123), SNORD116-20 (ENSG00000278715)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.