SNORD116-2

Summary

SNORD116-2 (small nucleolar RNA, C/D box 116-2, HGNC:33068) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033414 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33068
Approved symbol	SNORD116-2
Name	small nucleolar RNA, C/D box 116-2
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-85-2
Ensembl gene	ENSG00000207001
Ensembl biotype	snoRNA
Entrez	100033414
RNAcentral	URS000075D5DD — snoRNA, 97 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384274

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384274 — 1 exons

Exon	Start	End
ENSE00001809004	25054210	25054304

Expression profiles

Bgee: expression breadth broad, 52 present calls, max score 99.50.

Top tissues by expression

52 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.50	gold quality
liver	UBERON:0002107	96.42	gold quality
kidney	UBERON:0002113	96.31	gold quality
adult mammalian kidney	UBERON:0000082	95.57	gold quality
adrenal tissue	UBERON:0018303	95.16	gold quality
lung	UBERON:0002048	95.09	gold quality
stomach	UBERON:0000945	89.22	gold quality
blood	UBERON:0000178	87.59	gold quality
heart	UBERON:0000948	87.57	gold quality
intestine	UBERON:0000160	79.67	gold quality
frontal cortex	UBERON:0001870	75.76	gold quality
calcaneal tendon	UBERON:0003701	75.10	gold quality
endometrium	UBERON:0001295	74.61	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.05	gold quality
muscle of leg	UBERON:0001383	72.95	gold quality
colon	UBERON:0001155	72.47	gold quality
heart left ventricle	UBERON:0002084	70.87	gold quality
body of stomach	UBERON:0001161	70.50	gold quality
nucleus accumbens	UBERON:0001882	69.26	gold quality
vagina	UBERON:0000996	67.03	gold quality
gastrocnemius	UBERON:0001388	66.65	gold quality
small intestine	UBERON:0002108	66.40	gold quality
right atrium auricular region	UBERON:0006631	65.90	gold quality
subcutaneous adipose tissue	UBERON:0002190	65.56	gold quality
transverse colon	UBERON:0001157	65.33	gold quality
putamen	UBERON:0001874	64.70	gold quality
substantia nigra	UBERON:0002038	61.89	gold quality
skin of leg	UBERON:0001511	61.72	gold quality
tibial artery	UBERON:0007610	61.68	gold quality
left adrenal gland	UBERON:0001234	61.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.21

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (32): SNORD116-10 (ENSG00000200661), SNORD116 (ENSG00000202498), SNORD116-11 (ENSG00000206609), SNORD116-14 (ENSG00000206621), SNORD116-17 (ENSG00000206656), SNORD116-18 (ENSG00000206688), SNORD116-9 (ENSG00000206727), SNORD116-3 (ENSG00000207014), SNORD116-1 (ENSG00000207063), SNORD116-8 (ENSG00000207093), SNORD116-7 (ENSG00000207133), SNORD116-13 (ENSG00000207137), SNORD116-15 (ENSG00000207174), SNORD116-5 (ENSG00000207191), SNORD116-12 (ENSG00000207197), SNORD116-29 (ENSG00000207245), SNORD116-16 (ENSG00000207263), SNORD116-24 (ENSG00000207279), SNORD116-23 (ENSG00000207375), SNORD116-6 (ENSG00000207442), SNORD116-19 (ENSG00000207460), SNORD116 (ENSG00000212553), SNORD116-26 (ENSG00000251815), SNORD116-27 (ENSG00000251896), SNORD116-30 (ENSG00000252277), SNORD116-25 (ENSG00000252326), SNORD116 (ENSG00000252985), SNORD116-22 (ENSG00000275127), SNORD116-4 (ENSG00000275529), SNORD116-21 (ENSG00000277785), SNORD116-28 (ENSG00000278123), SNORD116-20 (ENSG00000278715)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.