SNORD116-21

Summary

SNORD116-21 (small nucleolar RNA, C/D box 116-21, HGNC:33087) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033432 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33087
Approved symbol	SNORD116-21
Name	small nucleolar RNA, C/D box 116-21
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-85-21
Ensembl gene	ENSG00000277785
Ensembl biotype	snoRNA
Entrez	100033432
RNAcentral	URS000075AF3E — snoRNA, 94 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384507

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384507 — 1 exons

Exon	Start	End
ENSE00001806845	25088804	25088895

Expression profiles

Bgee: expression breadth broad, 54 present calls, max score 97.17.

Top tissues by expression

54 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	97.17	gold quality
adrenal tissue	UBERON:0018303	88.40	gold quality
vermiform appendix	UBERON:0001154	85.38	gold quality
liver	UBERON:0002107	82.11	gold quality
stomach	UBERON:0000945	81.94	gold quality
lung	UBERON:0002048	81.72	gold quality
blood	UBERON:0000178	77.09	gold quality
Brodmann (1909) area 9	UBERON:0013540	76.43	gold quality
heart	UBERON:0000948	70.91	gold quality
prostate gland	UBERON:0002367	69.36	gold quality
muscle of leg	UBERON:0001383	67.71	gold quality
tibial artery	UBERON:0007610	67.25	gold quality
pancreas	UBERON:0001264	66.41	gold quality
gastrocnemius	UBERON:0001388	66.34	gold quality
tibial nerve	UBERON:0001323	65.82	gold quality
kidney	UBERON:0002113	64.11	gold quality
islet of Langerhans	UBERON:0000006	63.38	gold quality
intestine	UBERON:0000160	63.13	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	63.00	gold quality
thyroid gland	UBERON:0002046	62.80	gold quality
small intestine Peyer’s patch	UBERON:0003454	61.64	gold quality
Ammon’s horn	UBERON:0001954	61.41	gold quality
esophagus mucosa	UBERON:0002469	59.52	gold quality
right atrium auricular region	UBERON:0006631	59.35	gold quality
endometrium	UBERON:0001295	58.95	silver quality
heart left ventricle	UBERON:0002084	58.76	gold quality
body of stomach	UBERON:0001161	58.58	gold quality
omental fat pad	UBERON:0010414	58.57	gold quality
skeletal muscle tissue	UBERON:0001134	57.72	silver quality
lower esophagus muscularis layer	UBERON:0035833	57.72	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (32): SNORD116-10 (ENSG00000200661), SNORD116 (ENSG00000202498), SNORD116-11 (ENSG00000206609), SNORD116-14 (ENSG00000206621), SNORD116-17 (ENSG00000206656), SNORD116-18 (ENSG00000206688), SNORD116-9 (ENSG00000206727), SNORD116-2 (ENSG00000207001), SNORD116-3 (ENSG00000207014), SNORD116-1 (ENSG00000207063), SNORD116-8 (ENSG00000207093), SNORD116-7 (ENSG00000207133), SNORD116-13 (ENSG00000207137), SNORD116-15 (ENSG00000207174), SNORD116-5 (ENSG00000207191), SNORD116-12 (ENSG00000207197), SNORD116-29 (ENSG00000207245), SNORD116-16 (ENSG00000207263), SNORD116-24 (ENSG00000207279), SNORD116-23 (ENSG00000207375), SNORD116-6 (ENSG00000207442), SNORD116-19 (ENSG00000207460), SNORD116 (ENSG00000212553), SNORD116-26 (ENSG00000251815), SNORD116-27 (ENSG00000251896), SNORD116-30 (ENSG00000252277), SNORD116-25 (ENSG00000252326), SNORD116 (ENSG00000252985), SNORD116-22 (ENSG00000275127), SNORD116-4 (ENSG00000275529), SNORD116-28 (ENSG00000278123), SNORD116-20 (ENSG00000278715)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.