SNORD116-25

Summary

SNORD116-25 (small nucleolar RNA, C/D box 116-25, HGNC:33091) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033436 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33091
Approved symbol	SNORD116-25
Name	small nucleolar RNA, C/D box 116-25
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-85-25
Ensembl gene	ENSG00000252326
Ensembl biotype	snoRNA
Entrez	100033436
RNAcentral	URS000075A82F — snoRNA, 94 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000516517

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000516517 — 1 exons

Exon	Start	End
ENSE00002088794	25097663	25097754

Expression profiles

Bgee: expression breadth broad, 48 present calls, max score 98.84.

Top tissues by expression

48 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	98.84	gold quality
lung	UBERON:0002048	92.34	gold quality
adrenal tissue	UBERON:0018303	89.36	gold quality
liver	UBERON:0002107	88.68	gold quality
heart	UBERON:0000948	87.36	gold quality
kidney	UBERON:0002113	87.32	gold quality
tibial nerve	UBERON:0001323	87.19	gold quality
stomach	UBERON:0000945	85.62	gold quality
adult mammalian kidney	UBERON:0000082	80.91	gold quality
blood	UBERON:0000178	78.01	gold quality
Brodmann (1909) area 9	UBERON:0013540	76.24	gold quality
intestine	UBERON:0000160	75.67	gold quality
body of stomach	UBERON:0001161	75.45	gold quality
body of pancreas	UBERON:0001150	74.95	gold quality
caudate nucleus	UBERON:0001873	74.55	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	74.19	gold quality
lower esophagus muscularis layer	UBERON:0035833	72.69	gold quality
calcaneal tendon	UBERON:0003701	71.70	gold quality
right lobe of thyroid gland	UBERON:0001119	71.44	gold quality
substantia nigra	UBERON:0002038	70.42	gold quality
ascending aorta	UBERON:0001496	68.47	gold quality
amygdala	UBERON:0001876	68.14	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	68.14	gold quality
Ammon’s horn	UBERON:0001954	67.18	gold quality
colon	UBERON:0001155	66.69	gold quality
muscle layer of sigmoid colon	UBERON:0035805	65.91	gold quality
right atrium auricular region	UBERON:0006631	65.85	gold quality
hypothalamus	UBERON:0001898	65.22	gold quality
vagina	UBERON:0000996	65.20	gold quality
brain	UBERON:0000955	64.37	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.78

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm22373	ENSMUSG00000077772
rattus_norvegicus	LOC120100337	ENSRNOG00000053202

Paralogs (32): SNORD116-10 (ENSG00000200661), SNORD116 (ENSG00000202498), SNORD116-11 (ENSG00000206609), SNORD116-14 (ENSG00000206621), SNORD116-17 (ENSG00000206656), SNORD116-18 (ENSG00000206688), SNORD116-9 (ENSG00000206727), SNORD116-2 (ENSG00000207001), SNORD116-3 (ENSG00000207014), SNORD116-1 (ENSG00000207063), SNORD116-8 (ENSG00000207093), SNORD116-7 (ENSG00000207133), SNORD116-13 (ENSG00000207137), SNORD116-15 (ENSG00000207174), SNORD116-5 (ENSG00000207191), SNORD116-12 (ENSG00000207197), SNORD116-29 (ENSG00000207245), SNORD116-16 (ENSG00000207263), SNORD116-24 (ENSG00000207279), SNORD116-23 (ENSG00000207375), SNORD116-6 (ENSG00000207442), SNORD116-19 (ENSG00000207460), SNORD116 (ENSG00000212553), SNORD116-26 (ENSG00000251815), SNORD116-27 (ENSG00000251896), SNORD116-30 (ENSG00000252277), SNORD116 (ENSG00000252985), SNORD116-22 (ENSG00000275127), SNORD116-4 (ENSG00000275529), SNORD116-21 (ENSG00000277785), SNORD116-28 (ENSG00000278123), SNORD116-20 (ENSG00000278715)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.