SNORD116-28

Summary

SNORD116-28 (small nucleolar RNA, C/D box 116-28, HGNC:33347) is a small nucleolar RNA gene on chromosome 15q11.2.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33347
Approved symbol	SNORD116-28
Name	small nucleolar RNA, C/D box 116-28
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-85-28
Ensembl gene	ENSG00000278123
Ensembl biotype	snoRNA
Entrez	100033820
RNAcentral	URS000075D211 — snoRNA, 93 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000516123

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000516123 — 1 exons

Exon	Start	End
ENSE00002088400	25104642	25104732

Expression profiles

Bgee: expression breadth broad, 36 present calls, max score 78.16.

Top tissues by expression

36 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	78.16	gold quality
muscle of leg	UBERON:0001383	75.57	gold quality
right atrium auricular region	UBERON:0006631	72.78	gold quality
caudate nucleus	UBERON:0001873	72.17	gold quality
body of pancreas	UBERON:0001150	72.06	gold quality
gastrocnemius	UBERON:0001388	71.54	gold quality
tibial nerve	UBERON:0001323	70.85	gold quality
muscle layer of sigmoid colon	UBERON:0035805	70.07	gold quality
esophagus mucosa	UBERON:0002469	69.53	gold quality
colon	UBERON:0001155	68.77	gold quality
esophagus	UBERON:0001043	68.48	gold quality
left adrenal gland cortex	UBERON:0035825	68.42	gold quality
transverse colon	UBERON:0001157	68.12	gold quality
body of stomach	UBERON:0001161	67.41	gold quality
skin of abdomen	UBERON:0001416	66.28	gold quality
blood	UBERON:0000178	65.38	gold quality
heart	UBERON:0000948	64.36	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	64.24	gold quality
putamen	UBERON:0001874	64.09	gold quality
right adrenal gland	UBERON:0001233	63.91	gold quality
skin of leg	UBERON:0001511	63.62	gold quality
omental fat pad	UBERON:0010414	63.61	gold quality
right frontal lobe	UBERON:0002810	63.04	gold quality
thoracic aorta	UBERON:0001515	62.47	gold quality
lung	UBERON:0002048	61.72	gold quality
small intestine Peyer’s patch	UBERON:0003454	59.84	gold quality
upper lobe of left lung	UBERON:0008952	59.45	gold quality
adenohypophysis	UBERON:0002196	59.30	gold quality
ascending aorta	UBERON:0001496	58.78	gold quality
right hemisphere of cerebellum	UBERON:0014890	57.22	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm22373	ENSMUSG00000077772
rattus_norvegicus	LOC120100337	ENSRNOG00000053202

Paralogs (32): SNORD116-10 (ENSG00000200661), SNORD116 (ENSG00000202498), SNORD116-11 (ENSG00000206609), SNORD116-14 (ENSG00000206621), SNORD116-17 (ENSG00000206656), SNORD116-18 (ENSG00000206688), SNORD116-9 (ENSG00000206727), SNORD116-2 (ENSG00000207001), SNORD116-3 (ENSG00000207014), SNORD116-1 (ENSG00000207063), SNORD116-8 (ENSG00000207093), SNORD116-7 (ENSG00000207133), SNORD116-13 (ENSG00000207137), SNORD116-15 (ENSG00000207174), SNORD116-5 (ENSG00000207191), SNORD116-12 (ENSG00000207197), SNORD116-29 (ENSG00000207245), SNORD116-16 (ENSG00000207263), SNORD116-24 (ENSG00000207279), SNORD116-23 (ENSG00000207375), SNORD116-6 (ENSG00000207442), SNORD116-19 (ENSG00000207460), SNORD116 (ENSG00000212553), SNORD116-26 (ENSG00000251815), SNORD116-27 (ENSG00000251896), SNORD116-30 (ENSG00000252277), SNORD116-25 (ENSG00000252326), SNORD116 (ENSG00000252985), SNORD116-22 (ENSG00000275127), SNORD116-4 (ENSG00000275529), SNORD116-21 (ENSG00000277785), SNORD116-20 (ENSG00000278715)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.