SNORD116-4

Summary

SNORD116-4 (small nucleolar RNA, C/D box 116-4, HGNC:33070) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033416 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33070
Approved symbol	SNORD116-4
Name	small nucleolar RNA, C/D box 116-4
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-85-4
Ensembl gene	ENSG00000275529
Ensembl biotype	snoRNA
Entrez	100033416
RNAcentral	URS000075E49E — snoRNA, 98 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384733

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384733 — 1 exons

Exon	Start	End
ENSE00001809182	25059538	25059633

Expression profiles

Bgee: expression breadth broad, 64 present calls, max score 85.70.

Top tissues by expression

64 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	85.70	gold quality
skeletal muscle tissue	UBERON:0001134	82.72	gold quality
liver	UBERON:0002107	78.67	gold quality
right adrenal gland	UBERON:0001233	74.98	gold quality
adult mammalian kidney	UBERON:0000082	72.48	gold quality
blood	UBERON:0000178	71.82	gold quality
prostate gland	UBERON:0002367	70.77	gold quality
muscle of leg	UBERON:0001383	69.72	gold quality
islet of Langerhans	UBERON:0000006	69.32	gold quality
heart left ventricle	UBERON:0002084	68.49	gold quality
adrenal gland	UBERON:0002369	67.13	gold quality
gastrocnemius	UBERON:0001388	66.99	gold quality
body of uterus	UBERON:0009853	66.25	gold quality
endometrium	UBERON:0001295	65.89	gold quality
right ovary	UBERON:0002118	65.08	gold quality
adrenal tissue	UBERON:0018303	64.64	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.18	gold quality
hypothalamus	UBERON:0001898	63.62	gold quality
body of pancreas	UBERON:0001150	63.52	gold quality
left adrenal gland	UBERON:0001234	63.28	gold quality
left adrenal gland cortex	UBERON:0035825	62.68	gold quality
tibial artery	UBERON:0007610	62.48	gold quality
transverse colon	UBERON:0001157	61.98	gold quality
heart	UBERON:0000948	61.53	gold quality
leukocyte	CL:0000738	61.33	gold quality
right lobe of thyroid gland	UBERON:0001119	61.29	gold quality
amygdala	UBERON:0001876	60.89	gold quality
anterior cingulate cortex	UBERON:0009835	60.58	gold quality
putamen	UBERON:0001874	60.51	gold quality
minor salivary gland	UBERON:0001830	60.49	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (32): SNORD116-10 (ENSG00000200661), SNORD116 (ENSG00000202498), SNORD116-11 (ENSG00000206609), SNORD116-14 (ENSG00000206621), SNORD116-17 (ENSG00000206656), SNORD116-18 (ENSG00000206688), SNORD116-9 (ENSG00000206727), SNORD116-2 (ENSG00000207001), SNORD116-3 (ENSG00000207014), SNORD116-1 (ENSG00000207063), SNORD116-8 (ENSG00000207093), SNORD116-7 (ENSG00000207133), SNORD116-13 (ENSG00000207137), SNORD116-15 (ENSG00000207174), SNORD116-5 (ENSG00000207191), SNORD116-12 (ENSG00000207197), SNORD116-29 (ENSG00000207245), SNORD116-16 (ENSG00000207263), SNORD116-24 (ENSG00000207279), SNORD116-23 (ENSG00000207375), SNORD116-6 (ENSG00000207442), SNORD116-19 (ENSG00000207460), SNORD116 (ENSG00000212553), SNORD116-26 (ENSG00000251815), SNORD116-27 (ENSG00000251896), SNORD116-30 (ENSG00000252277), SNORD116-25 (ENSG00000252326), SNORD116 (ENSG00000252985), SNORD116-22 (ENSG00000275127), SNORD116-21 (ENSG00000277785), SNORD116-28 (ENSG00000278123), SNORD116-20 (ENSG00000278715)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.