SNORD116-8

Summary

SNORD116-8 (small nucleolar RNA, C/D box 116-8, HGNC:33074) is a small nucleolar RNA gene on chromosome 15q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100033420 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33074
Approved symbol	SNORD116-8
Name	small nucleolar RNA, C/D box 116-8
Location	15q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-85-8
Ensembl gene	ENSG00000207093
Ensembl biotype	snoRNA
Entrez	100033420
RNAcentral	URS000075EAB9 — snoRNA, 97 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384365

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384365 — 1 exons

Exon	Start	End
ENSE00001808228	25070432	25070526

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 99.70.

Top tissues by expression

78 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.70	gold quality
adult mammalian kidney	UBERON:0000082	98.57	gold quality
adrenal tissue	UBERON:0018303	98.16	gold quality
liver	UBERON:0002107	93.10	gold quality
kidney	UBERON:0002113	91.62	gold quality
blood	UBERON:0000178	88.25	gold quality
lung	UBERON:0002048	85.90	gold quality
stomach	UBERON:0000945	84.08	gold quality
skeletal muscle tissue	UBERON:0001134	83.44	gold quality
calcaneal tendon	UBERON:0003701	79.51	gold quality
heart	UBERON:0000948	77.88	gold quality
islet of Langerhans	UBERON:0000006	77.73	gold quality
Brodmann (1909) area 9	UBERON:0013540	76.00	gold quality
muscle of leg	UBERON:0001383	75.63	gold quality
gastrocnemius	UBERON:0001388	75.60	gold quality
intestine	UBERON:0000160	74.06	gold quality
endometrium	UBERON:0001295	72.77	gold quality
right atrium auricular region	UBERON:0006631	72.36	gold quality
body of stomach	UBERON:0001161	70.11	gold quality
body of pancreas	UBERON:0001150	70.02	gold quality
tibial nerve	UBERON:0001323	70.02	gold quality
right adrenal gland cortex	UBERON:0035827	69.65	gold quality
left coronary artery	UBERON:0001626	69.54	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	69.50	gold quality
colon	UBERON:0001155	69.42	gold quality
thoracic aorta	UBERON:0001515	68.22	gold quality
hypothalamus	UBERON:0001898	68.11	gold quality
heart left ventricle	UBERON:0002084	67.96	gold quality
ascending aorta	UBERON:0001496	67.87	gold quality
vagina	UBERON:0000996	67.47	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (32): SNORD116-10 (ENSG00000200661), SNORD116 (ENSG00000202498), SNORD116-11 (ENSG00000206609), SNORD116-14 (ENSG00000206621), SNORD116-17 (ENSG00000206656), SNORD116-18 (ENSG00000206688), SNORD116-9 (ENSG00000206727), SNORD116-2 (ENSG00000207001), SNORD116-3 (ENSG00000207014), SNORD116-1 (ENSG00000207063), SNORD116-7 (ENSG00000207133), SNORD116-13 (ENSG00000207137), SNORD116-15 (ENSG00000207174), SNORD116-5 (ENSG00000207191), SNORD116-12 (ENSG00000207197), SNORD116-29 (ENSG00000207245), SNORD116-16 (ENSG00000207263), SNORD116-24 (ENSG00000207279), SNORD116-23 (ENSG00000207375), SNORD116-6 (ENSG00000207442), SNORD116-19 (ENSG00000207460), SNORD116 (ENSG00000212553), SNORD116-26 (ENSG00000251815), SNORD116-27 (ENSG00000251896), SNORD116-30 (ENSG00000252277), SNORD116-25 (ENSG00000252326), SNORD116 (ENSG00000252985), SNORD116-22 (ENSG00000275127), SNORD116-4 (ENSG00000275529), SNORD116-21 (ENSG00000277785), SNORD116-28 (ENSG00000278123), SNORD116-20 (ENSG00000278715)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.