SNORD11B

Summary

SNORD11B (small nucleolar RNA, C/D box 11B, HGNC:33571) is a small nucleolar RNA gene on chromosome 2q33.1.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100113392 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33571
Approved symbol	SNORD11B
Name	small nucleolar RNA, C/D box 11B
Location	2q33.1
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000271852
Ensembl biotype	snoRNA
Entrez	100113392
RNAcentral	URS000075ED7D — snoRNA, 112 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000607707

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000607707 — 1 exons

Exon	Start	End
ENSE00003698014	202291332	202291421

Expression profiles

Bgee: expression breadth broad, 86 present calls, max score 92.09.

Top tissues by expression

86 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
calcaneal tendon	UBERON:0003701	92.09	gold quality
sural nerve	UBERON:0015488	87.19	gold quality
skeletal muscle tissue	UBERON:0001134	85.07	gold quality
adrenal tissue	UBERON:0018303	85.02	gold quality
duodenum	UBERON:0002114	79.64	gold quality
kidney	UBERON:0002113	79.59	gold quality
endometrium	UBERON:0001295	79.49	gold quality
liver	UBERON:0002107	78.80	gold quality
muscle of leg	UBERON:0001383	77.01	gold quality
monocyte	CL:0000576	76.86	gold quality
stomach	UBERON:0000945	75.87	gold quality
bone marrow	UBERON:0002371	75.84	gold quality
blood	UBERON:0000178	75.68	gold quality
placenta	UBERON:0001987	75.60	gold quality
corpus callosum	UBERON:0002336	75.49	gold quality
gastrocnemius	UBERON:0001388	73.13	gold quality
adrenal gland	UBERON:0002369	72.73	gold quality
heart	UBERON:0000948	72.71	gold quality
heart left ventricle	UBERON:0002084	71.36	gold quality
islet of Langerhans	UBERON:0000006	71.35	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	71.26	gold quality
body of pancreas	UBERON:0001150	69.75	gold quality
intestine	UBERON:0000160	69.74	gold quality
fundus of stomach	UBERON:0001160	69.44	gold quality
body of stomach	UBERON:0001161	68.99	gold quality
right atrium auricular region	UBERON:0006631	68.92	gold quality
adult mammalian kidney	UBERON:0000082	68.65	gold quality
colon	UBERON:0001155	68.48	gold quality
right lobe of liver	UBERON:0001114	68.31	gold quality
transverse colon	UBERON:0001157	68.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.87

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• SNORD11B-mediated 2’-O-methylation of primary let-7a in colorectal carcinogenesis. (PMID:37620450)

Cross-species orthologs

4 orthologs

Organism	Symbol	Gene ID
danio_rerio		ENSDARG00000085291
danio_rerio		ENSDARG00000085557
mus_musculus	Gm26287	ENSMUSG00000089512
rattus_norvegicus	Snord11b	ENSRNOG00000056779

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.