SNORD126

Summary

SNORD126 (small nucleolar RNA, C/D box 126, HGNC:33565) is a small nucleolar RNA gene on chromosome 14q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100113391 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33565
Approved symbol	SNORD126
Name	small nucleolar RNA, C/D box 126
Location	14q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	hsa-mir-1201
Ensembl gene	ENSG00000238344
Ensembl biotype	snoRNA
Entrez	100113391
RNAcentral	URS0000759F95 — snoRNA, 99 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000459475

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000459475 — 1 exons

Exon	Start	End
ENSE00001807726	20326450	20326526

Expression profiles

Bgee: expression breadth broad, 75 present calls, max score 93.38.

Top tissues by expression

75 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	93.38	gold quality
liver	UBERON:0002107	83.10	gold quality
calcaneal tendon	UBERON:0003701	81.15	gold quality
adrenal tissue	UBERON:0018303	80.19	gold quality
adrenal gland	UBERON:0002369	78.28	gold quality
monocyte	CL:0000576	77.39	gold quality
stomach	UBERON:0000945	77.04	gold quality
fundus of stomach	UBERON:0001160	75.37	gold quality
blood	UBERON:0000178	74.81	gold quality
bone marrow	UBERON:0002371	74.73	gold quality
gastrocnemius	UBERON:0001388	72.36	gold quality
islet of Langerhans	UBERON:0000006	72.14	gold quality
endometrium	UBERON:0001295	71.78	gold quality
kidney	UBERON:0002113	71.37	gold quality
adult mammalian kidney	UBERON:0000082	70.67	gold quality
heart	UBERON:0000948	70.30	gold quality
lung	UBERON:0002048	70.21	gold quality
left coronary artery	UBERON:0001626	68.78	gold quality
endocervix	UBERON:0000458	68.76	gold quality
right lobe of liver	UBERON:0001114	68.67	gold quality
intestine	UBERON:0000160	68.62	gold quality
Brodmann (1909) area 9	UBERON:0013540	68.43	gold quality
left adrenal gland	UBERON:0001234	68.39	gold quality
heart left ventricle	UBERON:0002084	68.17	gold quality
rectum	UBERON:0001052	68.13	gold quality
body of stomach	UBERON:0001161	67.75	gold quality
right atrium auricular region	UBERON:0006631	67.64	gold quality
body of pancreas	UBERON:0001150	67.48	gold quality
popliteal artery	UBERON:0002250	67.40	gold quality
tibial artery	UBERON:0007610	67.23	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.66

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• SNORD126 is highly expressed in hepatocellular carcinoma and colorectal cancer patient samples.SNORD126 activates the PI3K-AKT pathway by upregulation of FGFR2.SNORD126 facilitates tumour cell growth and confers resistance to chemotherapy. (PMID:27913571)

Cross-species orthologs

1 orthologs

Organism	Symbol	Gene ID
rattus_norvegicus	LOC120097276	ENSRNOG00000058479

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.