SNORD127

Summary

SNORD127 (small nucleolar RNA, C/D box 127, HGNC:33555) is a small nucleolar RNA gene on chromosome 14q21.3.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100113389 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33555
Approved symbol	SNORD127
Name	small nucleolar RNA, C/D box 127
Location	14q21.3
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000239043
Ensembl biotype	snoRNA
Entrez	100113389
RNAcentral	URS000075CB76 — snoRNA, 101 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000458892

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000458892 — 1 exons

Exon	Start	End
ENSE00001808409	45110883	45110968

Expression profiles

Bgee: expression breadth ubiquitous, 106 present calls, max score 99.11.

Top tissues by expression

106 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.11	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.54	gold quality
adrenal tissue	UBERON:0018303	87.34	gold quality
skeletal muscle tissue	UBERON:0001134	85.42	gold quality
endometrium	UBERON:0001295	84.22	gold quality
calcaneal tendon	UBERON:0003701	84.17	gold quality
placenta	UBERON:0001987	82.66	gold quality
bone marrow	UBERON:0002371	82.13	gold quality
vermiform appendix	UBERON:0001154	81.55	gold quality
duodenum	UBERON:0002114	80.51	gold quality
monocyte	CL:0000576	78.07	gold quality
blood	UBERON:0000178	76.58	gold quality
liver	UBERON:0002107	76.34	gold quality
muscle of leg	UBERON:0001383	75.24	gold quality
kidney	UBERON:0002113	75.18	gold quality
adult mammalian kidney	UBERON:0000082	74.80	gold quality
Brodmann (1909) area 9	UBERON:0013540	74.05	gold quality
lymph node	UBERON:0000029	73.74	gold quality
gastrocnemius	UBERON:0001388	73.74	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	72.38	gold quality
stomach	UBERON:0000945	72.36	gold quality
mucosa of stomach	UBERON:0001199	72.25	gold quality
left adrenal gland cortex	UBERON:0035825	72.20	gold quality
corpus callosum	UBERON:0002336	72.19	gold quality
islet of Langerhans	UBERON:0000006	72.02	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.98	gold quality
adrenal gland	UBERON:0002369	71.75	gold quality
rectum	UBERON:0001052	71.62	gold quality
cerebellar hemisphere	UBERON:0002245	71.58	gold quality
right adrenal gland	UBERON:0001233	71.29	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm25970	ENSMUSG00000087790
rattus_norvegicus	Snord127	ENSRNOG00000055941

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.