SNORD134

Summary

SNORD134 (small nucleolar RNA, C/D box 134, HGNC:50415) is a gene on chromosome 17q25.3.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50415
Approved symbol	SNORD134
Name	small nucleolar RNA, C/D box 134
Location	17q25.3
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ZL12
Entrez	106633803
RNAcentral	URS00008E3A70 — snoRNA, 181 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000960709 (17:82090231 C>T), RS1003453855 (17:82091466 T>C), RS1004521385 (17:82089978 G>A,T), RS1004591366 (17:82090862 G>A,C), RS1005561405 (17:82091734 G>T), RS1006588345 (17:82092089 G>A,T), RS1008757132 (17:82090315 C>G), RS1009600538 (17:82090146 C>T), RS1009899437 (17:82091285 G>A,C,T), RS1011839173 (17:82092108 C>G,T), RS1012169701 (17:82091337 A>G), RS1013847950 (17:82090425 C>A,T), RS1014065387 (17:82089786 C>A,T), RS1014594827 (17:82089573 C>A,T), RS1015721080 (17:82090598 T>A,C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Smoke	decreases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.