SNORD135

Summary

SNORD135 (small nucleolar RNA, C/D box 135, HGNC:50416) is a gene on chromosome 19p13.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 106633804 — RefSeq curated summary.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50416
Approved symbol	SNORD135
Name	small nucleolar RNA, C/D box 135
Location	19p13.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ZL2
Entrez	106633804
RNAcentral	URS00008E3980 — snoRNA, 75 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000509369 (19:12703176 A>T), RS1002333062 (19:12703147 T>C,G), RS1003884241 (19:12704007 G>A), RS1005516989 (19:12705459 A>T), RS1007276253 (19:12705155 T>C), RS1008370068 (19:12703182 G>A,T), RS1008583079 (19:12703533 G>A), RS1009726782 (19:12703396 G>A), RS1009972783 (19:12704536 A>G), RS1013694985 (19:12704617 AC>A), RS1014148689 (19:12704413 T>C), RS1015516964 (19:12703709 C>T), RS1015816734 (19:12703317 G>A,T), RS1017611803 (19:12705054 T>G), RS1018548792 (19:12705164 A>G)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.