SNORD136

Summary

SNORD136 (small nucleolar RNA, C/D box 136, HGNC:50417) is a gene on chromosome 3p21.1.

At a glance

• GWAS associations: 3

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50417
Approved symbol	SNORD136
Name	small nucleolar RNA, C/D box 136
Location	3p21.1
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ZL26
Entrez	106633805
RNAcentral	URS00008E3A6E — snoRNA, 147 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1004621323 (3:52687815 C>A,G,T), RS1005015433 (3:52688538 G>T), RS1009364130 (3:52688403 C>T), RS1009921872 (3:52686892 T>TG), RS1011544527 (3:52689025 G>A,T), RS1012329464 (3:52687746 C>G), RS1012662466 (3:52689451 A>G,T), RS1014579701 (3:52687466 T>C,G), RS1014695358 (3:52687841 G>A,T), RS1018381810 (3:52687011 A>G), RS1021685147 (3:52688687 AC>A), RS1022067375 (3:52688680 C>T), RS1022119553 (3:52688405 C>T), RS1027243529 (3:52689427 T>A), RS1027777197 (3:52687748 T>A,C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

3 associations (top):

Study	Trait	p-value
GCST004521_123	Autism spectrum disorder or schizophrenia	3.000000e-12
GCST004521_201	Autism spectrum disorder or schizophrenia	4.000000e-08
GCST004521_259	Autism spectrum disorder or schizophrenia	6.000000e-09

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.