SNORD141B

Summary

SNORD141B (small nucleolar RNA, C/D box 141B, HGNC:51407) is a gene on chromosome 5p15.2.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51407
Approved symbol	SNORD141B
Name	small nucleolar RNA, C/D box 141B
Location	5p15.2
Locus type	RNA, small nucleolar
Status	Approved
Entrez	106635684
RNAcentral	URS00008E397A — snoRNA, 105 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1001429871 (5:14651915 G>A), RS1003072440 (5:14653058 G>A,C), RS1003105153 (5:14653250 T>C), RS1004365651 (5:14653367 G>A,T), RS1008978024 (5:14652048 G>A), RS1010933176 (5:14652629 T>A), RS1014418157 (5:14654262 G>C), RS1014480174 (5:14653570 A>G), RS1016964876 (5:14653770 G>A), RS1016966944 (5:14654300 T>G), RS1018997346 (5:14652072 G>A,T), RS1020546402 (5:14652645 G>A), RS1020666741 (5:14652985 C>T), RS1020809815 (5:14653897 TAGAA>T), RS1022894426 (5:14653571 T>A,C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Smoke	decreases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.