SNORD143

Summary

SNORD143 (small nucleolar RNA, C/D box 143, HGNC:50400) is a gene on chromosome 4q21.22.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50400
Approved symbol	SNORD143
Name	small nucleolar RNA, C/D box 143
Location	4q21.22
Locus type	RNA, small nucleolar
Status	Approved
Aliases	ZL5
Entrez	106633808
RNAcentral	URS0000A76B4D — snoRNA, 76 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000424435 (4:82897477 G>A), RS1000815276 (4:82895706 C>A,T), RS1002929956 (4:82895809 C>T), RS1003308853 (4:82897611 T>C), RS1009860189 (4:82895363 G>C), RS1010632429 (4:82896674 G>A,C), RS1011082486 (4:82896947 C>G), RS1011964132 (4:82897266 C>T), RS1012610945 (4:82897440 A>G), RS1013410583 (4:82896205 T>C), RS1013563298 (4:82895519 T>TA), RS1014046044 (4:82895781 C>T), RS1016925243 (4:82895903 G>A), RS1017770522 (4:82896378 C>T), RS1018203470 (4:82896856 A>G)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.