SNORD14E

Summary

SNORD14E (small nucleolar RNA, C/D box 14E, HGNC:30354) is a small nucleolar RNA gene on chromosome 11q23.3-q25.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:30354
Approved symbol	SNORD14E
Name	small nucleolar RNA, C/D box 14E
Location	11q23.3-q25
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000200879
Ensembl biotype	snoRNA
Entrez	85391
RNAcentral	URS000081501D — snoRNA, 85 nt, 12 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364009

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364009 — 1 exons

Exon	Start	End
ENSE00001438772	123058077	123058161

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 99.53.

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	99.53	gold quality
corpus callosum	UBERON:0002336	98.81	gold quality
lower esophagus mucosa	UBERON:0035834	98.70	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	96.90	gold quality
adrenal tissue	UBERON:0018303	95.21	gold quality
mucosa of transverse colon	UBERON:0004991	94.97	gold quality
right lobe of liver	UBERON:0001114	94.46	gold quality
sural nerve	UBERON:0015488	94.45	gold quality
liver	UBERON:0002107	94.18	gold quality
endometrium	UBERON:0001295	93.77	gold quality
pituitary gland	UBERON:0000007	93.44	gold quality
right hemisphere of cerebellum	UBERON:0014890	93.38	gold quality
metanephros cortex	UBERON:0010533	92.97	gold quality
adenohypophysis	UBERON:0002196	92.26	gold quality
cerebellar hemisphere	UBERON:0002245	91.98	gold quality
adult mammalian kidney	UBERON:0000082	91.69	gold quality
substantia nigra	UBERON:0002038	91.55	gold quality
hypothalamus	UBERON:0001898	91.31	gold quality
apex of heart	UBERON:0002098	91.09	gold quality
caudate nucleus	UBERON:0001873	91.06	gold quality
Ammon’s horn	UBERON:0001954	90.84	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	90.76	gold quality
kidney	UBERON:0002113	90.63	gold quality
duodenum	UBERON:0002114	90.19	gold quality
putamen	UBERON:0001874	89.96	gold quality
brain	UBERON:0000955	89.94	gold quality
amygdala	UBERON:0001876	89.80	gold quality
vermiform appendix	UBERON:0001154	89.52	gold quality
nucleus accumbens	UBERON:0001882	89.13	gold quality
anterior cingulate cortex	UBERON:0009835	89.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.61

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Prognostic value of small nucleolar RNAs (snoRNAs) for colon adenocarcinoma based on RNA sequencing data. (PMID:32312483)

Cross-species orthologs

1 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord14e	ENSMUSG00002076818

Paralogs (5): SNORD14B (ENSG00000201403), SNORD14C (ENSG00000202252), SNORD14 (ENSG00000202479), SNORD14D (ENSG00000207118), SNORD14A (ENSG00000272034)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.