SNORD159

Summary

SNORD159 (small nucleolar RNA, C/D box 159, HGNC:51873) is a gene on chromosome 21q22.3.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51873
Approved symbol	SNORD159
Name	small nucleolar RNA, C/D box 159
Location	21q22.3
Locus type	RNA, small nucleolar
Status	Approved
Entrez	109623452
RNAcentral	URS0000ABD86B — snoRNA, 70 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000278232 (21:46193850 T>C), RS1000288262 (21:46193681 G>A,C), RS1003037866 (21:46195468 G>A), RS1003476269 (21:46195341 A>G), RS1005438476 (21:46194370 C>G), RS1006153507 (21:46195130 C>A,T), RS1006434924 (21:46195356 A>G), RS1007480499 (21:46195062 G>A), RS1009579092 (21:46193930 G>T), RS1010682795 (21:46193659 C>T), RS1011970115 (21:46194018 CTG>C), RS1012412408 (21:46194287 C>T), RS1012516302 (21:46193911 C>G), RS1013110582 (21:46194952 C>T), RS1016231570 (21:46195142 A>C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
versicolorin A	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.