SNORD15A

Summary

SNORD15A (small nucleolar RNA, C/D box 15A, HGNC:10114) is a small nucleolar RNA gene on chromosome 11q13.4.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 6079 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10114
Approved symbol	SNORD15A
Name	small nucleolar RNA, C/D box 15A
Location	11q13.4
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U15A
Ensembl gene	ENSG00000206941
Ensembl biotype	snoRNA
OMIM	600455
Entrez	6079
RNAcentral	URS00003A9200 — snoRNA, 148 nt, 7 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384214

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384214 — 1 exons

Exon	Start	End
ENSE00001499223	75400391	75400538

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 99.56.

Top tissues by expression

111 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.56	gold quality
adrenal tissue	UBERON:0018303	97.85	gold quality
liver	UBERON:0002107	81.04	gold quality
superior frontal gyrus	UBERON:0002661	79.36	gold quality
corpus callosum	UBERON:0002336	78.24	gold quality
blood	UBERON:0000178	77.53	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	77.10	gold quality
kidney	UBERON:0002113	76.83	gold quality
ectocervix	UBERON:0012249	76.04	gold quality
monocyte	CL:0000576	74.35	gold quality
bone marrow	UBERON:0002371	74.11	gold quality
lung	UBERON:0002048	73.75	gold quality
adult mammalian kidney	UBERON:0000082	73.48	gold quality
ascending aorta	UBERON:0001496	73.05	gold quality
left coronary artery	UBERON:0001626	72.40	gold quality
prefrontal cortex	UBERON:0000451	72.35	gold quality
thoracic aorta	UBERON:0001515	72.22	gold quality
smooth muscle tissue	UBERON:0001135	72.16	gold quality
stomach	UBERON:0000945	71.95	gold quality
left ovary	UBERON:0002119	71.71	gold quality
vagina	UBERON:0000996	71.40	gold quality
ovary	UBERON:0000992	70.95	gold quality
heart	UBERON:0000948	70.92	gold quality
gastrocnemius	UBERON:0001388	70.82	gold quality
lower esophagus mucosa	UBERON:0035834	70.49	gold quality
muscle of leg	UBERON:0001383	70.43	gold quality
right lobe of liver	UBERON:0001114	70.40	gold quality
tibial artery	UBERON:0007610	70.11	gold quality
popliteal artery	UBERON:0002250	70.07	gold quality
lymph node	UBERON:0000029	69.53	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.31

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer’s disease. (PMID:34411703)

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord15a	ENSMUSG00000065822
rattus_norvegicus	Snord15a	ENSRNOG00000052293

Paralogs (1): SNORD15B (ENSG00000207445)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.