SNORD15B

Summary

SNORD15B (small nucleolar RNA, C/D box 15B, HGNC:16649) is a small nucleolar RNA gene on chromosome 11q13.4.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 114599 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16649
Approved symbol	SNORD15B
Name	small nucleolar RNA, C/D box 15B
Location	11q13.4
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U15B
Ensembl gene	ENSG00000207445
Ensembl biotype	snoRNA
Entrez	114599
RNAcentral	URS000043549A — snoRNA, 146 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384714

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384714 — 1 exons

Exon	Start	End
ENSE00001499722	75404421	75404566

Expression profiles

Bgee: expression breadth ubiquitous, 114 present calls, max score 99.64.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.5475 / max 162.8225, expressed in 966 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
115899	3.5475	966

Top tissues by expression

114 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adrenal tissue	UBERON:0018303	99.64	gold quality
sural nerve	UBERON:0015488	99.63	gold quality
granulocyte	CL:0000094	89.71	gold quality
monocyte	CL:0000576	87.68	gold quality
bone marrow	UBERON:0002371	86.29	gold quality
right ovary	UBERON:0002118	85.04	gold quality
blood	UBERON:0000178	82.93	gold quality
ectocervix	UBERON:0012249	82.46	gold quality
lower esophagus mucosa	UBERON:0035834	81.97	gold quality
ovary	UBERON:0000992	81.58	gold quality
left ovary	UBERON:0002119	81.27	gold quality
liver	UBERON:0002107	81.04	gold quality
skin of abdomen	UBERON:0001416	78.98	gold quality
lung	UBERON:0002048	78.69	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	78.34	gold quality
spleen	UBERON:0002106	78.31	gold quality
esophagus mucosa	UBERON:0002469	78.19	gold quality
stomach	UBERON:0000945	78.09	gold quality
kidney	UBERON:0002113	77.97	gold quality
myometrium	UBERON:0001296	77.82	gold quality
calcaneal tendon	UBERON:0003701	77.58	gold quality
vagina	UBERON:0000996	77.47	gold quality
omental fat pad	UBERON:0010414	77.21	gold quality
mucosa of transverse colon	UBERON:0004991	76.82	gold quality
primary visual cortex	UBERON:0002436	76.81	gold quality
endocervix	UBERON:0000458	76.66	gold quality
right coronary artery	UBERON:0001625	76.36	gold quality
zone of skin	UBERON:0000014	76.10	gold quality
upper lobe of left lung	UBERON:0008952	76.04	gold quality
fundus of stomach	UBERON:0001160	75.85	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.56

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer’s disease. (PMID:34411703)

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord15b	ENSMUSG00000064966
rattus_norvegicus	Snord15b	ENSRNOG00000055569

Paralogs (1): SNORD15A (ENSG00000206941)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.