SNORD1C

Summary

SNORD1C (small nucleolar RNA, C/D box 1C, HGNC:32677) is a small nucleolar RNA gene on chromosome 17q25.1.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 677850 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32677
Approved symbol	SNORD1C
Name	small nucleolar RNA, C/D box 1C
Location	17q25.1
Locus type	RNA, small nucleolar
Status	Approved
Aliases	R38C, snR38C
Ensembl gene	ENSG00000274091
Ensembl biotype	snoRNA
Entrez	677850
RNAcentral	URS0000ABD829 — snoRNA, 80 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000363315

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000363315 — 1 exons

Exon	Start	End
ENSE00001438078	76558791	76558868

Expression profiles

Bgee: expression breadth broad, 36 present calls, max score 98.13.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6945 / max 54.2742, expressed in 401 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
162875	0.6945	401

Top tissues by expression

36 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	98.13	gold quality
calcaneal tendon	UBERON:0003701	89.41	gold quality
muscle of leg	UBERON:0001383	84.69	gold quality
liver	UBERON:0002107	83.95	gold quality
tibial nerve	UBERON:0001323	83.86	gold quality
adrenal tissue	UBERON:0018303	81.30	gold quality
heart	UBERON:0000948	80.60	gold quality
blood	UBERON:0000178	77.49	gold quality
lung	UBERON:0002048	75.95	gold quality
multicellular organism	UBERON:0000468	71.92	gold quality
Brodmann (1909) area 9	UBERON:0013540	71.48	gold quality
stomach	UBERON:0000945	69.49	gold quality
body of stomach	UBERON:0001161	69.43	gold quality
gastrocnemius	UBERON:0001388	67.85	gold quality
left adrenal gland cortex	UBERON:0035825	65.70	gold quality
putamen	UBERON:0001874	65.37	gold quality
heart left ventricle	UBERON:0002084	64.09	gold quality
amygdala	UBERON:0001876	63.86	gold quality
intestine	UBERON:0000160	62.53	gold quality
nucleus accumbens	UBERON:0001882	61.61	gold quality
transverse colon	UBERON:0001157	61.12	gold quality
right frontal lobe	UBERON:0002810	60.93	gold quality
colon	UBERON:0001155	60.66	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	59.94	gold quality
spleen	UBERON:0002106	59.70	gold quality
muscle layer of sigmoid colon	UBERON:0035805	57.00	gold quality
substantia nigra	UBERON:0002038	56.17	gold quality
pituitary gland	UBERON:0000007	54.93	gold quality
left ovary	UBERON:0002119	54.03	gold quality
skin of abdomen	UBERON:0001416	51.06	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Overexpression of small nucleolar RNA SNORD1C is associated with unfavorable outcome in colorectal cancer. (PMID:34702132)

Cross-species orthologs

5 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm24253	ENSMUSG00000065635
mus_musculus	Snord1c	ENSMUSG00000065640
mus_musculus	Snord1b	ENSMUSG00000077604
rattus_norvegicus	Snord1b	ENSRNOG00000082596
rattus_norvegicus		ENSRNOG00000090321

Paralogs (2): SNORD1B (ENSG00000199961), SNORD1A (ENSG00000278261)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.