SNORD22

Summary

SNORD22 (small nucleolar RNA, C/D box 22, HGNC:10145) is a small nucleolar RNA gene on chromosome 11q13.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 9304 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10145
Approved symbol	SNORD22
Name	small nucleolar RNA, C/D box 22
Location	11q13
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U22
Ensembl gene	ENSG00000277194
Ensembl biotype	snoRNA
OMIM	603223
Entrez	9304
RNAcentral	URS000066FABB — snoRNA, 126 nt, 8 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384756

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384756 — 1 exons

Exon	Start	End
ENSE00001499764	62852910	62853035

Expression profiles

Bgee: expression breadth broad, 43 present calls, max score 99.81.

Top tissues by expression

43 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.81	gold quality
adult mammalian kidney	UBERON:0000082	99.60	gold quality
intestine	UBERON:0000160	99.33	gold quality
colon	UBERON:0001155	99.28	gold quality
liver	UBERON:0002107	99.24	gold quality
adrenal tissue	UBERON:0018303	98.64	gold quality
stomach	UBERON:0000945	95.46	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	93.83	gold quality
heart	UBERON:0000948	93.27	gold quality
lung	UBERON:0002048	91.97	gold quality
kidney	UBERON:0002113	91.96	gold quality
tibial nerve	UBERON:0001323	90.22	gold quality
adrenal gland	UBERON:0002369	89.97	gold quality
blood	UBERON:0000178	87.71	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.58	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	84.20	gold quality
calcaneal tendon	UBERON:0003701	83.41	gold quality
multicellular organism	UBERON:0000468	82.86	gold quality
skin of leg	UBERON:0001511	77.47	gold quality
skeletal muscle tissue	UBERON:0001134	76.15	gold quality
left lobe of thyroid gland	UBERON:0001120	72.91	gold quality
heart left ventricle	UBERON:0002084	72.86	gold quality
body of stomach	UBERON:0001161	70.56	gold quality
adipose tissue	UBERON:0001013	69.63	gold quality
muscle of leg	UBERON:0001383	68.10	gold quality
islet of Langerhans	UBERON:0000006	66.47	gold quality
nucleus accumbens	UBERON:0001882	66.31	gold quality
hypothalamus	UBERON:0001898	66.11	gold quality
subcutaneous adipose tissue	UBERON:0002190	65.93	gold quality
Ammon’s horn	UBERON:0001954	64.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

4 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord22	ENSMUSG00000065087
rattus_norvegicus	LOC120100233	ENSRNOG00000056397
rattus_norvegicus	LOC120101999	ENSRNOG00000057313
rattus_norvegicus	Snord22	ENSRNOG00000060760

Paralogs (1): SNORD22 (ENSG00000278527)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.