SNORD25

Summary

SNORD25 (small nucleolar RNA, C/D box 25, HGNC:10147) is a small nucleolar RNA gene on chromosome 11q13.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 9303 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10147
Approved symbol	SNORD25
Name	small nucleolar RNA, C/D box 25
Location	11q13
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U25
Ensembl gene	ENSG00000275043
Ensembl biotype	snoRNA
OMIM	603224
Entrez	9303
RNAcentral	URS0000454FD5 — ncRNA, 67 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000365607

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000365607 — 1 exons

Exon	Start	End
ENSE00001440370	62855564	62855632

Expression profiles

Bgee: expression breadth broad, 12 present calls, max score 98.15.

Top tissues by expression

12 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	98.15	gold quality
liver	UBERON:0002107	97.43	gold quality
muscle of leg	UBERON:0001383	78.66	gold quality
blood	UBERON:0000178	76.37	gold quality
Brodmann (1909) area 9	UBERON:0013540	74.54	gold quality
adult mammalian kidney	UBERON:0000082	69.99	gold quality
nucleus accumbens	UBERON:0001882	67.02	gold quality
skeletal muscle tissue	UBERON:0001134	65.11	gold quality
monocyte	CL:0000576	64.40	gold quality
Ammon’s horn	UBERON:0001954	63.03	gold quality
prefrontal cortex	UBERON:0000451	60.02	gold quality
vermiform appendix	UBERON:0001154	54.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Overexpression of SNORD25 is associated with high-risk smoldering multiple myeloma. (PMID:22331267)

Cross-species orthologs

1 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm25855	ENSMUSG00000064721

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.