SNORD28

Summary

SNORD28 (small nucleolar RNA, C/D box 28, HGNC:10150) is a small nucleolar RNA gene on chromosome 11q12.3.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 9300 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10150
Approved symbol	SNORD28
Name	small nucleolar RNA, C/D box 28
Location	11q12.3
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U28, SNORD28A
Ensembl gene	ENSG00000274544
Ensembl biotype	snoRNA
OMIM	603227
Entrez	9300
RNAcentral	URS000015A7CF — snoRNA, 75 nt, 8 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384706

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384706 — 1 exons

Exon	Start	End
ENSE00001499714	62854621	62854695

Expression profiles

Bgee: expression breadth broad, 21 present calls, max score 99.20.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5288 / max 25.1162, expressed in 302 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
120253	0.5288	302

Top tissues by expression

21 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.20	gold quality
lung	UBERON:0002048	93.25	gold quality
liver	UBERON:0002107	91.71	gold quality
adrenal tissue	UBERON:0018303	84.48	gold quality
stomach	UBERON:0000945	78.68	gold quality
heart	UBERON:0000948	78.37	gold quality
blood	UBERON:0000178	77.44	gold quality
kidney	UBERON:0002113	76.80	gold quality
nucleus accumbens	UBERON:0001882	73.90	gold quality
adult mammalian kidney	UBERON:0000082	71.32	gold quality
Brodmann (1909) area 9	UBERON:0013540	71.00	gold quality
intestine	UBERON:0000160	69.11	gold quality
heart left ventricle	UBERON:0002084	68.13	gold quality
calcaneal tendon	UBERON:0003701	67.75	gold quality
skin of leg	UBERON:0001511	66.00	gold quality
hypothalamus	UBERON:0001898	58.04	gold quality
monocyte	CL:0000576	56.77	gold quality
gastrocnemius	UBERON:0001388	56.15	gold quality
lower esophagus muscularis layer	UBERON:0035833	55.76	gold quality
amygdala	UBERON:0001876	49.89	gold quality
smooth muscle tissue	UBERON:0001135	41.63	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Gm24453	ENSMUSG00000065280
rattus_norvegicus	Snord28b	ENSRNOG00000060156

Paralogs (2): SNORD28B (ENSG00000212295), SNORA108 (ENSG00000252284)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.