SNORD28B

Summary

SNORD28B (small nucleolar RNA, C/D box 28B, HGNC:52225) is a small nucleolar RNA gene on chromosome 6q25.3.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 109617011 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52225
Approved symbol	SNORD28B
Name	small nucleolar RNA, C/D box 28B
Location	6q25.3
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000212295
Ensembl biotype	snoRNA
Entrez	109617011
RNAcentral	URS000067F09E — snoRNA, 75 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000390993

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000390993 — 1 exons

Exon	Start	End
ENSE00001508777	156378750	156378824

Expression profiles

Bgee: expression breadth broad, 28 present calls, max score 83.29.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1836 / max 54.2742, expressed in 52 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
204267	0.1836	52

Top tissues by expression

28 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	83.29	gold quality
lymph node	UBERON:0000029	81.44	gold quality
endometrium	UBERON:0001295	73.95	gold quality
stomach	UBERON:0000945	72.20	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	72.14	gold quality
heart left ventricle	UBERON:0002084	70.70	gold quality
intestine	UBERON:0000160	70.25	gold quality
tonsil	UBERON:0002372	70.04	gold quality
body of stomach	UBERON:0001161	69.90	gold quality
subcutaneous adipose tissue	UBERON:0002190	68.80	gold quality
right frontal lobe	UBERON:0002810	68.57	gold quality
omental fat pad	UBERON:0010414	68.46	gold quality
right lobe of thyroid gland	UBERON:0001119	67.63	gold quality
zone of skin	UBERON:0000014	64.89	gold quality
skin of leg	UBERON:0001511	64.81	gold quality
skin of abdomen	UBERON:0001416	64.72	gold quality
esophagus mucosa	UBERON:0002469	63.85	gold quality
thyroid gland	UBERON:0002046	63.03	gold quality
minor salivary gland	UBERON:0001830	62.97	gold quality
left lobe of thyroid gland	UBERON:0001120	62.23	gold quality
corpus callosum	UBERON:0002336	60.23	gold quality
pituitary gland	UBERON:0000007	59.92	gold quality
right ovary	UBERON:0002118	59.51	gold quality
body of uterus	UBERON:0009853	58.83	gold quality
small intestine Peyer’s patch	UBERON:0003454	57.45	gold quality
spleen	UBERON:0002106	55.56	gold quality
left testis	UBERON:0004533	46.05	gold quality
right testis	UBERON:0004534	38.86	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.21

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (2): SNORA108 (ENSG00000252284), SNORD28 (ENSG00000274544)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.