SNORD30

Summary

SNORD30 (small nucleolar RNA, C/D box 30, HGNC:10157) is a small nucleolar RNA gene on chromosome 11q12.3.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 9299 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10157
Approved symbol	SNORD30
Name	small nucleolar RNA, C/D box 30
Location	11q12.3
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U30
Ensembl gene	ENSG00000277846
Ensembl biotype	snoRNA
OMIM	603229
Entrez	9299
RNAcentral	URS00004E0FA9 — snoRNA, 70 nt, 8 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384693

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384693 — 1 exons

Exon	Start	End
ENSE00001499701	62853663	62853732

Expression profiles

Bgee: expression breadth broad, 22 present calls, max score 95.34.

Top tissues by expression

22 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	95.34	gold quality
liver	UBERON:0002107	93.89	gold quality
stomach	UBERON:0000945	85.09	gold quality
lung	UBERON:0002048	78.27	gold quality
blood	UBERON:0000178	77.31	gold quality
colon	UBERON:0001155	77.29	gold quality
heart	UBERON:0000948	76.84	gold quality
monocyte	CL:0000576	76.82	gold quality
adult mammalian kidney	UBERON:0000082	75.06	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.79	gold quality
adrenal tissue	UBERON:0018303	72.01	gold quality
putamen	UBERON:0001874	70.37	gold quality
heart left ventricle	UBERON:0002084	68.90	gold quality
gastrocnemius	UBERON:0001388	68.21	gold quality
lower esophagus muscularis layer	UBERON:0035833	64.20	gold quality
anterior cingulate cortex	UBERON:0009835	62.65	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	59.50	gold quality
tibial artery	UBERON:0007610	57.59	gold quality
caudate nucleus	UBERON:0001873	54.17	gold quality
amygdala	UBERON:0001876	52.20	gold quality
substantia nigra	UBERON:0002038	48.99	gold quality
right frontal lobe	UBERON:0002810	36.27	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.71

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Overexpression of SNORD30 is associated with high-risk smoldering multiple myeloma. (PMID:22331267)

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
danio_rerio	snord30	ENSDARG00000080156
mus_musculus	Gm22680	ENSMUSG00000065782
rattus_norvegicus	Snord30	ENSRNOG00000061138

Paralogs (1): SNORD30 (ENSG00000212611)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.