SNORD35A

Summary

SNORD35A (small nucleolar RNA, C/D box 35A, HGNC:10162) is a small nucleolar RNA gene on chromosome 19q13.33.

Predicted to be involved in RNA processing. Predicted to act upstream of or within glucose metabolic process; insulin secretion; and reactive oxygen species metabolic process. Predicted to be located in nucleolus.

Source: NCBI Gene 26816 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10162
Approved symbol	SNORD35A
Name	small nucleolar RNA, C/D box 35A
Location	19q13.33
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U35, RNU35A
Ensembl gene	ENSG00000200259
Ensembl biotype	snoRNA
Entrez	26816
RNAcentral	URS000026935A — snoRNA, 86 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000363389

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000363389 — 1 exons

Exon	Start	End
ENSE00001438152	49491175	49491260

Expression profiles

Bgee: expression breadth broad, 34 present calls, max score 96.93.

FANTOM5 (CAGE): breadth broad, TPM avg 0.5743 / max 121.2753, expressed in 227 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
177000	0.5743	227

Top tissues by expression

34 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	96.93	gold quality
liver	UBERON:0002107	96.28	gold quality
adrenal tissue	UBERON:0018303	94.78	gold quality
heart	UBERON:0000948	89.70	gold quality
lung	UBERON:0002048	88.47	gold quality
blood	UBERON:0000178	85.17	gold quality
skeletal muscle tissue	UBERON:0001134	80.74	gold quality
duodenum	UBERON:0002114	79.29	gold quality
small intestine	UBERON:0002108	76.73	gold quality
kidney	UBERON:0002113	76.08	gold quality
muscle of leg	UBERON:0001383	73.47	gold quality
stomach	UBERON:0000945	71.52	gold quality
calcaneal tendon	UBERON:0003701	71.48	gold quality
intestine	UBERON:0000160	70.94	gold quality
prostate gland	UBERON:0002367	69.11	gold quality
Brodmann (1909) area 9	UBERON:0013540	68.62	gold quality
left adrenal gland	UBERON:0001234	68.39	gold quality
hypothalamus	UBERON:0001898	67.43	gold quality
putamen	UBERON:0001874	65.52	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	64.69	gold quality
nucleus accumbens	UBERON:0001882	63.87	gold quality
colon	UBERON:0001155	62.21	gold quality
gastrocnemius	UBERON:0001388	62.08	gold quality
anterior cingulate cortex	UBERON:0009835	61.45	gold quality
body of stomach	UBERON:0001161	57.91	gold quality
frontal cortex	UBERON:0001870	57.75	gold quality
adult mammalian kidney	UBERON:0000082	56.14	gold quality
right frontal lobe	UBERON:0002810	49.61	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.40	gold quality
caudate nucleus	UBERON:0001873	48.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord35a	ENSMUSG00000065818
rattus_norvegicus	Snord35a	ENSRNOG00000060031

Paralogs (1): SNORD35B (ENSG00000200530)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.