SNORD3E

Summary

SNORD3E (small nucleolar RNA, C/D box 3E, HGNC:52238) is a small nucleolar RNA gene on chromosome Xq13.1.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 109617015 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52238
Approved symbol	SNORD3E
Name	small nucleolar RNA, C/D box 3E
Location	Xq13.1
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000280704
Ensembl biotype	snoRNA
Entrez	109617015
RNAcentral	URS0000814588 — lncRNA, 215 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000627253

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000627253 — 1 exons

Exon	Start	End
ENSE00003764867	70846080	70846295

Expression profiles

Bgee: expression breadth ubiquitous, 113 present calls, max score 95.05.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2408 / max 54.1666, expressed in 96 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
199531	0.2408	96

Top tissues by expression

113 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.05	gold quality
corpus callosum	UBERON:0002336	81.98	gold quality
sural nerve	UBERON:0015488	80.33	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.27	gold quality
adrenal tissue	UBERON:0018303	72.96	gold quality
skeletal muscle tissue	UBERON:0001134	72.07	gold quality
bone marrow	UBERON:0002371	70.77	gold quality
monocyte	CL:0000576	69.36	gold quality
primary visual cortex	UBERON:0002436	69.15	gold quality
prefrontal cortex	UBERON:0000451	68.90	gold quality
lymph node	UBERON:0000029	68.77	gold quality
endometrium	UBERON:0001295	67.50	gold quality
muscle of leg	UBERON:0001383	67.29	gold quality
calcaneal tendon	UBERON:0003701	67.20	gold quality
blood	UBERON:0000178	66.91	gold quality
left uterine tube	UBERON:0001303	66.66	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	65.99	gold quality
gastrocnemius	UBERON:0001388	65.97	gold quality
duodenum	UBERON:0002114	65.28	gold quality
islet of Langerhans	UBERON:0000006	65.15	gold quality
liver	UBERON:0002107	64.85	gold quality
placenta	UBERON:0001987	64.01	gold quality
granulocyte	CL:0000094	63.93	gold quality
ectocervix	UBERON:0012249	63.37	gold quality
skin of abdomen	UBERON:0001416	63.31	gold quality
gall bladder	UBERON:0002110	62.61	gold quality
adrenal gland	UBERON:0002369	62.17	gold quality
zone of skin	UBERON:0000014	62.10	gold quality
left adrenal gland cortex	UBERON:0035825	61.80	gold quality
descending thoracic aorta	UBERON:0002345	61.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (55): U3 (ENSG00000199370), SNORD3G (ENSG00000199666), U3 (ENSG00000199851), U3 (ENSG00000199856), U3 (ENSG00000200222), SNORD3P1 (ENSG00000200318), U3 (ENSG00000200492), U3 (ENSG00000200538), U3 (ENSG00000200545), U3 (ENSG00000200693), U3 (ENSG00000201329), U3 (ENSG00000201346), U3 (ENSG00000201368), U3 (ENSG00000201674), U3 (ENSG00000202233), U3 (ENSG00000202268), U3 (ENSG00000207119), SNORD3H (ENSG00000207215), U3 (ENSG00000212165), U3 (ENSG00000212182), U3 (ENSG00000212195), U3 (ENSG00000212211), U3 (ENSG00000212321), U3 (ENSG00000212422), U3 (ENSG00000212434), U3 (ENSG00000212479), U3 (ENSG00000212511), U3 (ENSG00000212538), U3 (ENSG00000212539), U3 (ENSG00000212551), U3 (ENSG00000212598), U3 (ENSG00000212610), U3 (ENSG00000221040), U3 (ENSG00000221043), U3 (ENSG00000221044), U3 (ENSG00000221125), U3 (ENSG00000221332), U3 (ENSG00000221345), SNORD3J (ENSG00000221400), U3 (ENSG00000221455)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.