SNORD3F

Summary

SNORD3F (small nucleolar RNA, C/D box 3F, HGNC:52239) is a gene on chromosome 8p21.3.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 109616983 — RefSeq curated summary.

At a glance

• GWAS associations: 2

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52239
Approved symbol	SNORD3F
Name	small nucleolar RNA, C/D box 3F
Location	8p21.3
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U3, U3.2
Entrez	109616983
RNAcentral	URS0000A9C359 — snoRNA, 98 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000270373 (8:20616750 T>C), RS1001186140 (8:20616244 A>G), RS1001964442 (8:20615776 C>A,T), RS1002353312 (8:20616002 T>C), RS1003370132 (8:20614765 T>C), RS1004168637 (8:20616273 G>T), RS1004199843 (8:20616074 T>C), RS1004703519 (8:20616869 A>T), RS1005253897 (8:20615618 T>C,G), RS1005706785 (8:20615769 G>A,T), RS1007556078 (8:20615141 C>G), RS1008542701 (8:20614971 G>A,C), RS10086161 (8:20615236 C>A,G,T), RS1009486288 (8:20615816 T>G), RS10100654 (8:20615170 A>C,G,T)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

2 associations (top):

Study	Trait	p-value
GCST006996_1	Cerebrospinal AB1-42 levels in mild cognitive impairment	7.000000e-06
GCST007012_2	Cerebrospinal fluid AB1-42 levels	3.000000e-08

EFO canonical traits (1, from GWAS)

EFO ID	Trait name
EFO:0004670	beta-amyloid 1-42 measurement

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
aristolochic acid I	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.