SNORD42A

Summary

SNORD42A (small nucleolar RNA, C/D box 42A, HGNC:10180) is a small nucleolar RNA gene on chromosome 17q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 26809 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10180
Approved symbol	SNORD42A
Name	small nucleolar RNA, C/D box 42A
Location	17q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U42
Ensembl gene	ENSG00000238649
Ensembl biotype	snoRNA
Entrez	26809
RNAcentral	URS00022AE7D9 — snoRNA, 61 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000459584

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000459584 — 1 exons

Exon	Start	End
ENSE00001806818	28723429	28723492

Expression profiles

Bgee: expression breadth broad, 37 present calls, max score 99.62.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2124 / max 162.8225, expressed in 44 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
160059	0.2124	44

Top tissues by expression

37 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.62	gold quality
vermiform appendix	UBERON:0001154	91.11	gold quality
kidney	UBERON:0002113	87.83	gold quality
liver	UBERON:0002107	85.16	gold quality
Brodmann (1909) area 9	UBERON:0013540	81.30	gold quality
tibial nerve	UBERON:0001323	80.86	gold quality
stomach	UBERON:0000945	78.57	gold quality
calcaneal tendon	UBERON:0003701	76.15	gold quality
islet of Langerhans	UBERON:0000006	75.86	gold quality
lung	UBERON:0002048	74.24	gold quality
adrenal tissue	UBERON:0018303	73.01	gold quality
blood	UBERON:0000178	72.41	gold quality
heart left ventricle	UBERON:0002084	69.28	gold quality
heart	UBERON:0000948	68.74	gold quality
intestine	UBERON:0000160	68.07	gold quality
colon	UBERON:0001155	67.20	gold quality
gastrocnemius	UBERON:0001388	66.89	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	65.69	gold quality
right atrium auricular region	UBERON:0006631	60.19	gold quality
lower esophagus	UBERON:0013473	58.84	gold quality
transverse colon	UBERON:0001157	58.64	gold quality
substantia nigra	UBERON:0002038	58.36	gold quality
lower esophagus muscularis layer	UBERON:0035833	57.49	gold quality
popliteal artery	UBERON:0002250	56.96	gold quality
left adrenal gland	UBERON:0001234	56.87	gold quality
caudate nucleus	UBERON:0001873	56.36	gold quality
tibial artery	UBERON:0007610	56.34	gold quality
subcutaneous adipose tissue	UBERON:0002190	55.30	gold quality
ascending aorta	UBERON:0001496	54.35	gold quality
esophagus mucosa	UBERON:0002469	53.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord42a	ENSMUSG00000064540
rattus_norvegicus	Snord42a	ENSRNOG00000056377

Paralogs (3): SNORD42 (ENSG00000201209), SNORD42 (ENSG00000202440), SNORD42B (ENSG00000238423)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.