SNORD45B

Summary

SNORD45B (small nucleolar RNA, C/D box 45B, HGNC:10185) is a small nucleolar RNA gene on chromosome 1p31.1.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 26804 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10185
Approved symbol	SNORD45B
Name	small nucleolar RNA, C/D box 45B
Location	1p31.1
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U45b
Ensembl gene	ENSG00000201487
Ensembl biotype	snoRNA
Entrez	26804
RNAcentral	URS00002F8E76 — snoRNA, 71 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364617

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364617 — 1 exons

Exon	Start	End
ENSE00001808743	75789477	75789548

Expression profiles

Bgee: expression breadth broad, 17 present calls, max score 98.73.

Top tissues by expression

17 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	98.73	gold quality
liver	UBERON:0002107	90.09	gold quality
stomach	UBERON:0000945	85.76	gold quality
Brodmann (1909) area 9	UBERON:0013540	82.34	gold quality
muscle of leg	UBERON:0001383	81.86	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	79.39	gold quality
gastrocnemius	UBERON:0001388	79.19	gold quality
lung	UBERON:0002048	77.78	gold quality
cerebral cortex	UBERON:0000956	76.46	gold quality
Ammon’s horn	UBERON:0001954	71.86	gold quality
adult mammalian kidney	UBERON:0000082	67.54	gold quality
blood	UBERON:0000178	66.68	gold quality
islet of Langerhans	UBERON:0000006	60.52	gold quality
substantia nigra	UBERON:0002038	60.15	gold quality
putamen	UBERON:0001874	56.40	gold quality
caudate nucleus	UBERON:0001873	52.63	gold quality
testis	UBERON:0000473	39.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord45b	ENSMUSG00000064731
rattus_norvegicus	Snord45b	ENSRNOG00000060388

Paralogs (7): (ENSG00000200051), (ENSG00000200422), (ENSG00000200706), SNORD45C (ENSG00000206620), SNORD45A (ENSG00000207241), (ENSG00000252438), (ENSG00000276643)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.