SNORD49A

Summary

SNORD49A (small nucleolar RNA, C/D box 49A, HGNC:10189) is a small nucleolar RNA gene on chromosome 17p11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 26800 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10189
Approved symbol	SNORD49A
Name	small nucleolar RNA, C/D box 49A
Location	17p11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U49, U49A
Ensembl gene	ENSG00000277370
Ensembl biotype	snoRNA
Entrez	26800
RNAcentral	URS00003B08B2 — snoRNA, 71 nt, 7 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384229

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384229 — 1 exons

Exon	Start	End
ENSE00001499238	16440036	16440106

Expression profiles

Bgee: expression breadth broad, 13 present calls, max score 99.74.

Top tissues by expression

13 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	99.74	gold quality
sural nerve	UBERON:0015488	98.82	gold quality
lung	UBERON:0002048	92.23	gold quality
monocyte	CL:0000576	79.70	gold quality
blood	UBERON:0000178	71.81	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.95	gold quality
heart	UBERON:0000948	68.06	gold quality
gastrocnemius	UBERON:0001388	66.63	gold quality
adrenal tissue	UBERON:0018303	66.23	gold quality
brain	UBERON:0000955	62.08	gold quality
heart left ventricle	UBERON:0002084	61.47	gold quality
substantia nigra	UBERON:0002038	50.67	gold quality
nucleus accumbens	UBERON:0001882	49.37	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
		ENSDARG00000104878
mus_musculus	Snord49a	ENSMUSG00000065734
rattus_norvegicus	Snord49a	ENSRNOG00000058899

Paralogs (1): SNORD49B (ENSG00000277108)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.