SNORD49B

Summary

SNORD49B (small nucleolar RNA, C/D box 49B, HGNC:32721) is a small nucleolar RNA gene on chromosome 17p11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 692087 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32721
Approved symbol	SNORD49B
Name	small nucleolar RNA, C/D box 49B
Location	17p11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U49B
Ensembl gene	ENSG00000277108
Ensembl biotype	snoRNA
Entrez	692087
RNAcentral	URS000075B39E — snoRNA, 48 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000365172

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000365172 — 1 exons

Exon	Start	End
ENSE00001439935	16439505	16439576

Expression profiles

Bgee: expression breadth broad, 11 present calls, max score 98.13.

FANTOM5 (CAGE): breadth broad, TPM avg 1.2290 / max 40.1801, expressed in 512 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
159705	1.2290	512

Top tissues by expression

11 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	98.13	gold quality
placenta	UBERON:0001987	82.04	gold quality
spleen	UBERON:0002106	75.49	gold quality
urinary bladder	UBERON:0001255	73.44	gold quality
small intestine	UBERON:0002108	71.71	gold quality
sural nerve	UBERON:0015488	66.00	silver quality
gastrocnemius	UBERON:0001388	64.61	gold quality
blood	UBERON:0000178	63.73	gold quality
heart left ventricle	UBERON:0002084	62.64	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	58.97	gold quality
lung	UBERON:0002048	49.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
		ENSDARG00000104878
mus_musculus	Snord49b	ENSMUSG00000064437
rattus_norvegicus	Snord49b	ENSRNOG00000057240

Paralogs (1): SNORD49A (ENSG00000277370)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.