SNORD58B

Summary

SNORD58B (small nucleolar RNA, C/D box 58B, HGNC:10209) is a small nucleolar RNA gene on chromosome 18q21.1.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 26790 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10209
Approved symbol	SNORD58B
Name	small nucleolar RNA, C/D box 58B
Location	18q21.1
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U58b
Ensembl gene	ENSG00000271982
Ensembl biotype	snoRNA
Entrez	26790
RNAcentral	URS00004BB247 — snoRNA, 66 nt, 9 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000607313

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000607313 — 1 exons

Exon	Start	End
ENSE00003702333	49491664	49491729

Expression profiles

Bgee: expression breadth tissue_specific, 4 present calls, max score 99.13.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7033 / max 54.2742, expressed in 367 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
171913	0.7033	367

Top tissues by expression

4 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.13	gold quality
liver	UBERON:0002107	87.72	gold quality
Brodmann (1909) area 9	UBERON:0013540	78.38	gold quality
blood	UBERON:0000178	72.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord58b	ENSMUSG00000064871
mus_musculus	Gm22354	ENSMUSG00000065853
rattus_norvegicus	Snord58b	ENSRNOG00000058148

Paralogs (3): SNORD58C (ENSG00000202093), SNORD58A (ENSG00000206602), SNORD58 (ENSG00000212615)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.