SNORD59A

Summary

SNORD59A (small nucleolar RNA, C/D box 59A, HGNC:10210) is a small nucleolar RNA gene on chromosome 12q13.3.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 26789 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:10210
Approved symbol	SNORD59A
Name	small nucleolar RNA, C/D box 59A
Location	12q13.3
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U59
Ensembl gene	ENSG00000207031
Ensembl biotype	snoRNA
Entrez	26789
RNAcentral	URS00004BEE5E — snoRNA, 75 nt, 10 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384304

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384304 — 1 exons

Exon	Start	End
ENSE00001499313	56645027	56645101

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 99.78.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0811 / max 54.2742, expressed in 11 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
131562	0.0811	11

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.78	gold quality
bone marrow	UBERON:0002371	98.63	gold quality
skeletal muscle tissue	UBERON:0001134	98.12	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	97.24	gold quality
duodenum	UBERON:0002114	96.77	gold quality
vermiform appendix	UBERON:0001154	96.76	gold quality
rectum	UBERON:0001052	96.38	gold quality
granulocyte	CL:0000094	96.24	gold quality
transverse colon	UBERON:0001157	95.60	gold quality
monocyte	CL:0000576	95.26	gold quality
adrenal tissue	UBERON:0018303	95.05	gold quality
skin of abdomen	UBERON:0001416	94.77	gold quality
apex of heart	UBERON:0002098	94.52	gold quality
small intestine	UBERON:0002108	94.50	gold quality
intestine	UBERON:0000160	94.18	gold quality
endometrium	UBERON:0001295	94.17	gold quality
small intestine Peyer’s patch	UBERON:0003454	94.16	gold quality
zone of skin	UBERON:0000014	94.11	gold quality
colon	UBERON:0001155	93.97	gold quality
skin of leg	UBERON:0001511	93.83	gold quality
metanephros cortex	UBERON:0010533	93.60	gold quality
body of stomach	UBERON:0001161	92.90	gold quality
stomach	UBERON:0000945	92.86	gold quality
muscle layer of sigmoid colon	UBERON:0035805	91.98	gold quality
saliva-secreting gland	UBERON:0001044	91.97	gold quality
right lobe of thyroid gland	UBERON:0001119	91.94	gold quality
minor salivary gland	UBERON:0001830	91.93	gold quality
left lobe of thyroid gland	UBERON:0001120	91.55	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	91.44	gold quality
lung	UBERON:0002048	91.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.89

Regulation

Is transcription factor: no

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
danio_rerio		ENSDARG00000082833
mus_musculus	Snord59a	ENSMUSG00000064778
rattus_norvegicus	Snord59a	ENSRNOG00000058093

Paralogs (2): (ENSG00000252517), (ENSG00000252682)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.