SNORD65

Summary

SNORD65 (small nucleolar RNA, C/D box 65, HGNC:32726) is a small nucleolar RNA gene on chromosome 17p11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 692106 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32726
Approved symbol	SNORD65
Name	small nucleolar RNA, C/D box 65
Location	17p11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-135, SNORD65A
Ensembl gene	ENSG00000277512
Ensembl biotype	snoRNA
Entrez	692106
RNAcentral	URS00006B6C71 — snoRNA, 73 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000391079

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000391079 — 1 exons

Exon	Start	End
ENSE00001508863	16441226	16441298

Expression profiles

Bgee: expression breadth broad, 19 present calls, max score 95.16.

Top tissues by expression

19 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	95.16	gold quality
adrenal tissue	UBERON:0018303	94.04	gold quality
liver	UBERON:0002107	91.02	gold quality
stomach	UBERON:0000945	90.29	gold quality
lung	UBERON:0002048	86.21	gold quality
lymph node	UBERON:0000029	82.99	gold quality
heart	UBERON:0000948	82.13	gold quality
blood	UBERON:0000178	77.98	gold quality
kidney	UBERON:0002113	77.95	gold quality
hypothalamus	UBERON:0001898	76.84	gold quality
right frontal lobe	UBERON:0002810	76.80	gold quality
calcaneal tendon	UBERON:0003701	75.58	gold quality
muscle of leg	UBERON:0001383	74.09	gold quality
gastrocnemius	UBERON:0001388	69.95	gold quality
islet of Langerhans	UBERON:0000006	69.75	gold quality
skin of leg	UBERON:0001511	68.68	gold quality
brain	UBERON:0000955	62.87	gold quality
cerebral cortex	UBERON:0000956	60.52	gold quality
anterior cingulate cortex	UBERON:0009835	42.44	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

4 orthologs

Organism	Symbol	Gene ID
danio_rerio		ENSDARG00000080188
danio_rerio		ENSDARG00000080775
mus_musculus	Snord65	ENSMUSG00000077457
rattus_norvegicus	Snord65	ENSRNOG00000055640

Paralogs (4): (ENSG00000212191), (ENSG00000212229), SNORD65C (ENSG00000212264), SNORD65B (ENSG00000238936)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.