SNORD66

Summary

SNORD66 (small nucleolar RNA, C/D box 66, HGNC:32727) is a small nucleolar RNA gene on chromosome 3q27.1.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 692107 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32727
Approved symbol	SNORD66
Name	small nucleolar RNA, C/D box 66
Location	3q27.1
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-142
Ensembl gene	ENSG00000212158
Ensembl biotype	snoRNA
Entrez	692107
RNAcentral	URS00006A65B9 — snoRNA, 76 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000390856

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000390856 — 1 exons

Exon	Start	End
ENSE00001508640	184325696	184325771

Expression profiles

Bgee: expression breadth broad, 96 present calls, max score 99.74.

Top tissues by expression

96 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.74	gold quality
adrenal tissue	UBERON:0018303	91.29	gold quality
skeletal muscle tissue	UBERON:0001134	84.39	gold quality
vermiform appendix	UBERON:0001154	83.71	gold quality
liver	UBERON:0002107	80.71	gold quality
bone marrow	UBERON:0002371	79.61	gold quality
blood	UBERON:0000178	78.75	gold quality
calcaneal tendon	UBERON:0003701	77.09	gold quality
monocyte	CL:0000576	76.75	gold quality
muscle of leg	UBERON:0001383	74.69	gold quality
kidney	UBERON:0002113	74.42	gold quality
gastrocnemius	UBERON:0001388	73.95	gold quality
smooth muscle tissue	UBERON:0001135	73.92	gold quality
heart	UBERON:0000948	73.62	gold quality
adult mammalian kidney	UBERON:0000082	73.36	gold quality
stomach	UBERON:0000945	72.55	gold quality
endometrium	UBERON:0001295	72.01	gold quality
adrenal gland	UBERON:0002369	71.91	gold quality
islet of Langerhans	UBERON:0000006	71.69	gold quality
right atrium auricular region	UBERON:0006631	71.50	gold quality
lower esophagus mucosa	UBERON:0035834	71.47	gold quality
lung	UBERON:0002048	70.89	gold quality
body of stomach	UBERON:0001161	70.50	gold quality
gall bladder	UBERON:0002110	70.50	gold quality
heart left ventricle	UBERON:0002084	70.40	gold quality
left adrenal gland cortex	UBERON:0035825	70.16	gold quality
tonsil	UBERON:0002372	69.84	gold quality
prefrontal cortex	UBERON:0000451	69.81	gold quality
fundus of stomach	UBERON:0001160	69.73	gold quality
right lobe of liver	UBERON:0001114	69.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.29

Regulation

Is transcription factor: no

Cross-species orthologs

4 orthologs

Organism	Symbol	Gene ID
danio_rerio		ENSDARG00000080942
danio_rerio		ENSDARG00000084411
mus_musculus	Snord66	ENSMUSG00000077239
rattus_norvegicus	Snord66	ENSRNOG00000056119

Paralogs (1): (ENSG00000212532)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.