SNORD7

Summary

SNORD7 (small nucleolar RNA, C/D box 7, HGNC:32704) is a small nucleolar RNA gene on chromosome 17q12.

This gene encodes a spliceosomal small nuclear RNA that has orthologs in S. pombe and D. melanogaster. In S. pombe, this gene is required for site-specific 2’-O-methylation of U6 snRNA at position A41. While this is not an essential gene for S. pombe growth, loss of this gene’s function may result in a slight decrease in mRNA splicing efficiency.

Source: NCBI Gene 692076 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32704
Approved symbol	SNORD7
Name	small nucleolar RNA, C/D box 7
Location	17q12
Locus type	RNA, small nucleolar
Status	Approved
Aliases	Z30, mgU6-47
Ensembl gene	ENSG00000207297
Ensembl biotype	snoRNA
Entrez	692076
RNAcentral	URS00005D7632 — snoRNA, 97 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000384567

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000384567 — 1 exons

Exon	Start	End
ENSE00001499575	35573657	35573753

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 85.59.

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
olfactory segment of nasal mucosa	UBERON:0005386	85.59	gold quality
skeletal muscle tissue	UBERON:0001134	83.62	gold quality
endometrium	UBERON:0001295	80.96	gold quality
sural nerve	UBERON:0015488	79.24	gold quality
right uterine tube	UBERON:0001302	78.51	gold quality
duodenum	UBERON:0002114	78.37	gold quality
lower esophagus mucosa	UBERON:0035834	78.22	gold quality
liver	UBERON:0002107	78.19	gold quality
adrenal tissue	UBERON:0018303	78.17	gold quality
islet of Langerhans	UBERON:0000006	78.09	gold quality
blood	UBERON:0000178	77.45	gold quality
right coronary artery	UBERON:0001625	77.19	gold quality
vermiform appendix	UBERON:0001154	77.01	gold quality
right hemisphere of cerebellum	UBERON:0014890	76.24	gold quality
cerebellar hemisphere	UBERON:0002245	75.54	gold quality
placenta	UBERON:0001987	75.31	gold quality
muscle of leg	UBERON:0001383	75.07	gold quality
kidney	UBERON:0002113	74.84	gold quality
right lobe of liver	UBERON:0001114	74.52	gold quality
body of stomach	UBERON:0001161	74.32	gold quality
ectocervix	UBERON:0012249	74.17	gold quality
stomach	UBERON:0000945	73.89	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	73.57	gold quality
heart left ventricle	UBERON:0002084	73.37	gold quality
lymph node	UBERON:0000029	73.32	gold quality
adrenal gland	UBERON:0002369	73.27	gold quality
bone marrow	UBERON:0002371	73.27	gold quality
body of pancreas	UBERON:0001150	73.25	gold quality
left adrenal gland cortex	UBERON:0035825	73.25	gold quality
descending thoracic aorta	UBERON:0002345	73.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Cross-species orthologs

4 orthologs

Organism	Symbol	Gene ID
danio_rerio		ENSDARG00000081799
danio_rerio		ENSDARG00000081972
mus_musculus	Snord7	ENSMUSG00000065715
rattus_norvegicus	Snord7	ENSRNOG00000053353

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.