SNORD70B

Summary

SNORD70B (small nucleolar RNA, C/D box 70B, HGNC:52233) is a small nucleolar RNA gene on chromosome 2q33.1.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 109616995 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52233
Approved symbol	SNORD70B
Name	small nucleolar RNA, C/D box 70B
Location	2q33.1
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000212309
Ensembl biotype	snoRNA
Entrez	109616995
RNAcentral	URS0000ABD8C9 — snoRNA, 75 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000391007

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000391007 — 1 exons

Exon	Start	End
ENSE00001508791	202278108	202278192

Expression profiles

Bgee: expression breadth broad, 84 present calls, max score 99.20.

Top tissues by expression

84 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.20	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.55	gold quality
adrenal tissue	UBERON:0018303	86.59	gold quality
endometrium	UBERON:0001295	79.88	gold quality
bone marrow	UBERON:0002371	79.64	gold quality
blood	UBERON:0000178	78.23	gold quality
calcaneal tendon	UBERON:0003701	77.76	gold quality
monocyte	CL:0000576	75.21	gold quality
muscle of leg	UBERON:0001383	75.18	gold quality
rectum	UBERON:0001052	74.77	gold quality
lymph node	UBERON:0000029	74.39	gold quality
gastrocnemius	UBERON:0001388	74.16	gold quality
liver	UBERON:0002107	74.08	gold quality
stomach	UBERON:0000945	71.84	gold quality
islet of Langerhans	UBERON:0000006	71.17	gold quality
heart	UBERON:0000948	70.97	gold quality
heart left ventricle	UBERON:0002084	70.01	gold quality
right atrium auricular region	UBERON:0006631	69.79	gold quality
body of stomach	UBERON:0001161	69.48	gold quality
kidney	UBERON:0002113	69.43	gold quality
body of pancreas	UBERON:0001150	69.10	gold quality
tonsil	UBERON:0002372	68.40	gold quality
adult mammalian kidney	UBERON:0000082	67.92	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.51	gold quality
intestine	UBERON:0000160	67.38	gold quality
tibial artery	UBERON:0007610	67.01	gold quality
esophagus mucosa	UBERON:0002469	66.83	gold quality
left adrenal gland	UBERON:0001234	66.72	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	66.49	gold quality
multicellular organism	UBERON:0000468	66.21	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.68

Regulation

Is transcription factor: no

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
danio_rerio	SNORD70B	ENSDARG00000080938
mus_musculus	Gm26293	ENSMUSG00000077358
rattus_norvegicus	Snord70b	ENSRNOG00000051367

Paralogs (1): SNORD70 (ENSG00000212534)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.