SNORD71

Summary

SNORD71 (small nucleolar RNA, C/D box 71, HGNC:32732) is a small nucleolar RNA gene on chromosome 16q22.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 692111 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32732
Approved symbol	SNORD71
Name	small nucleolar RNA, C/D box 71
Location	16q22.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-239, hsa-mir-768
Ensembl gene	ENSG00000223224
Ensembl biotype	snoRNA
Entrez	692111
RNAcentral	URS00006A38AA — snoRNA, 86 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000411292

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411292 — 1 exons

Exon	Start	End
ENSE00001591110	71758402	71758487

Expression profiles

Bgee: expression breadth ubiquitous, 101 present calls, max score 99.64.

Top tissues by expression

101 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.64	gold quality
adrenal tissue	UBERON:0018303	95.25	gold quality
calcaneal tendon	UBERON:0003701	88.44	gold quality
corpus callosum	UBERON:0002336	88.21	gold quality
bone marrow	UBERON:0002371	86.69	gold quality
Brodmann (1909) area 9	UBERON:0013540	85.74	gold quality
liver	UBERON:0002107	82.81	gold quality
blood	UBERON:0000178	81.45	gold quality
monocyte	CL:0000576	79.52	gold quality
kidney	UBERON:0002113	78.33	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	77.66	gold quality
stomach	UBERON:0000945	76.49	gold quality
muscle of leg	UBERON:0001383	76.48	gold quality
gastrocnemius	UBERON:0001388	75.25	gold quality
endometrium	UBERON:0001295	74.62	gold quality
islet of Langerhans	UBERON:0000006	73.94	gold quality
rectum	UBERON:0001052	73.73	gold quality
prefrontal cortex	UBERON:0000451	73.21	gold quality
adrenal gland	UBERON:0002369	73.01	gold quality
gall bladder	UBERON:0002110	72.86	gold quality
heart	UBERON:0000948	72.50	gold quality
adult mammalian kidney	UBERON:0000082	72.29	gold quality
lung	UBERON:0002048	71.50	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	71.32	gold quality
lymph node	UBERON:0000029	70.97	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	70.96	gold quality
right atrium auricular region	UBERON:0006631	70.88	gold quality
body of stomach	UBERON:0001161	70.27	gold quality
myometrium	UBERON:0001296	69.97	gold quality
metanephros cortex	UBERON:0010533	69.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.75

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 3)

• results identify downregulation of miR-768-3p and subsequent upregulation of eIF4E as an important mechanism in addition to phosphorylation of eIF4E responsible for MEK/ERK-mediated enhancement of protein synthesis in melanoma (PMID:23770856)
• The present results suggested that abnormal elevated miR-768-3p in non-small cell lung carcinomas (NSCLC) tumors and cell lines played important roles in NSCLC carcinogenic progression, and the targeting of miR-768-3p might be a potential therapeutic strategy for the treatment of NSCLC. (PMID:29048613)
• Clinical significance of serum miR-768-3p in HBV-related hepatocellular carcinoma and its potential mechanism. (PMID:32712720)

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord71	ENSMUSG00000077549
rattus_norvegicus	Snord71	ENSRNOG00000059926

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.