SNORD74B

Summary

SNORD74B (small nucleolar RNA, C/D box 74B, HGNC:52234) is a small nucleolar RNA gene on chromosome 21q21.1.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 109617014 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52234
Approved symbol	SNORD74B
Name	small nucleolar RNA, C/D box 74B
Location	21q21.1
Locus type	RNA, small nucleolar
Status	Approved
Ensembl gene	ENSG00000201025
Ensembl biotype	snoRNA
Entrez	109617014
RNAcentral	URS000064D7D2 — snoRNA, 73 nt, 3 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000364155

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000364155 — 1 exons

Exon	Start	End
ENSE00001438918	16284696	16284768

Expression profiles

Bgee: expression breadth broad, 68 present calls, max score 88.51.

Top tissues by expression

68 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	88.51	gold quality
adrenal tissue	UBERON:0018303	86.69	gold quality
kidney	UBERON:0002113	86.45	gold quality
adult mammalian kidney	UBERON:0000082	79.64	gold quality
calcaneal tendon	UBERON:0003701	79.46	gold quality
muscle of leg	UBERON:0001383	77.72	gold quality
endometrium	UBERON:0001295	77.63	gold quality
stomach	UBERON:0000945	77.45	gold quality
liver	UBERON:0002107	75.85	gold quality
ectocervix	UBERON:0012249	74.32	gold quality
sural nerve	UBERON:0015488	74.09	gold quality
lung	UBERON:0002048	73.56	gold quality
heart left ventricle	UBERON:0002084	73.53	gold quality
intestine	UBERON:0000160	73.16	gold quality
gastrocnemius	UBERON:0001388	72.71	gold quality
heart	UBERON:0000948	72.60	gold quality
substantia nigra	UBERON:0002038	72.51	gold quality
putamen	UBERON:0001874	71.47	gold quality
right lobe of liver	UBERON:0001114	71.29	gold quality
colon	UBERON:0001155	71.22	gold quality
right atrium auricular region	UBERON:0006631	70.11	gold quality
transverse colon	UBERON:0001157	69.66	gold quality
tibial artery	UBERON:0007610	69.46	gold quality
endocervix	UBERON:0000458	68.77	gold quality
ascending aorta	UBERON:0001496	67.27	gold quality
corpus callosum	UBERON:0002336	67.22	gold quality
anterior cingulate cortex	UBERON:0009835	67.15	gold quality
amygdala	UBERON:0001876	66.92	gold quality
body of uterus	UBERON:0009853	66.90	gold quality
omental fat pad	UBERON:0010414	66.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

3 orthologs

Organism	Symbol	Gene ID
danio_rerio	snord74	ENSDARG00000083457
mus_musculus	Gm26224	ENSMUSG00000064440
rattus_norvegicus	LOC120096384	ENSRNOG00000054347

Paralogs (6): (ENSG00000200206), (ENSG00000200891), (ENSG00000200897), (ENSG00000200999), (ENSG00000201502), (ENSG00000201666)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.