SNORD83A

Summary

SNORD83A (small nucleolar RNA, C/D box 83A, HGNC:17131) is a small nucleolar RNA gene on chromosome 22q13.1.

Intronic regions of ribosomal protein genes can harbor noncoding small nucleolar RNAs (snoRNAs), like SNORD83A, which are generated during pre-mRNA processing. snoRNAs form part of the small nucleolar ribonucleoprotein particles (snoRNPs) involved in pre-rRNA processing and modification. snoRNAs of the box C/D class, like SNORD83A, function in 2-prime-O-ribose methylation of rRNAs (Duga et al., 2000 [PubMed 10684968]).

Source: NCBI Gene 116937 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:17131
Approved symbol	SNORD83A
Name	small nucleolar RNA, C/D box 83A
Location	22q13.1
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U83A
Ensembl gene	ENSG00000209482
Ensembl biotype	snoRNA
OMIM	611070
Entrez	116937
RNAcentral	URS000054DD16 — snoRNA, 95 nt, 4 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000386747

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000386747 — 1 exons

Exon	Start	End
ENSE00001501753	39315213	39315307

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 99.37.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	99.37	gold quality
sural nerve	UBERON:0015488	98.02	gold quality
granulocyte	CL:0000094	97.68	gold quality
adrenal tissue	UBERON:0018303	95.23	gold quality
bone marrow	UBERON:0002371	92.68	gold quality
skin of abdomen	UBERON:0001416	91.93	gold quality
body of pancreas	UBERON:0001150	91.52	gold quality
left uterine tube	UBERON:0001303	91.49	gold quality
zone of skin	UBERON:0000014	90.28	gold quality
lower esophagus mucosa	UBERON:0035834	89.74	gold quality
skin of leg	UBERON:0001511	89.30	gold quality
body of stomach	UBERON:0001161	89.13	gold quality
pancreas	UBERON:0001264	88.45	gold quality
right adrenal gland cortex	UBERON:0035827	88.45	gold quality
stomach	UBERON:0000945	88.44	gold quality
endometrium	UBERON:0001295	88.37	gold quality
right ovary	UBERON:0002118	88.33	gold quality
vermiform appendix	UBERON:0001154	87.83	gold quality
right adrenal gland	UBERON:0001233	87.83	gold quality
adrenal gland	UBERON:0002369	87.78	gold quality
left adrenal gland	UBERON:0001234	87.70	gold quality
thoracic mammary gland	UBERON:0005200	87.60	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	87.46	gold quality
monocyte	CL:0000576	87.44	gold quality
right lung	UBERON:0002167	87.28	gold quality
esophagus mucosa	UBERON:0002469	87.23	gold quality
left adrenal gland cortex	UBERON:0035825	87.02	gold quality
rectum	UBERON:0001052	86.74	gold quality
small intestine Peyer’s patch	UBERON:0003454	86.59	gold quality
lung	UBERON:0002048	86.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.22

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
danio_rerio	SNORD83A	ENSDARG00000083950
mus_musculus	Gm55357	ENSMUSG00002075255

Paralogs (2): SNORD83B (ENSG00000209480), (ENSG00000252945)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.