SNORD83B

Summary

SNORD83B (small nucleolar RNA, C/D box 83B, HGNC:17132) is a small nucleolar RNA gene on chromosome 22q13.1.

Intronic regions of ribosomal protein genes can harbor noncoding small nucleolar RNAs (snoRNAs), like SNORD83B, which are generated during pre-mRNA processing. snoRNAs form part of the small nucleolar ribonucleoprotein particles (snoRNPs) involved in pre-rRNA processing and modification. snoRNAs of the box C/D class, like SNORD83B, function in 2-prime-O-ribose methylation of rRNAs (Duga et al., 2000 [PubMed 10684968]).

Source: NCBI Gene 116938 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:17132
Approved symbol	SNORD83B
Name	small nucleolar RNA, C/D box 83B
Location	22q13.1
Locus type	RNA, small nucleolar
Status	Approved
Aliases	U83B
Ensembl gene	ENSG00000209480
Ensembl biotype	snoRNA
OMIM	611071
Entrez	116938
RNAcentral	URS000027315D — snoRNA, 93 nt, 10 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000386745

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000386745 — 1 exons

Exon	Start	End
ENSE00001501751	39313819	39313911

Expression profiles

Bgee: expression breadth broad, 40 present calls, max score 99.45.

Top tissues by expression

40 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.45	gold quality
adrenal tissue	UBERON:0018303	96.16	gold quality
adrenal gland	UBERON:0002369	94.27	gold quality
liver	UBERON:0002107	92.44	gold quality
lung	UBERON:0002048	83.25	gold quality
stomach	UBERON:0000945	80.11	gold quality
blood	UBERON:0000178	79.23	gold quality
monocyte	CL:0000576	78.32	gold quality
lymph node	UBERON:0000029	77.43	gold quality
intestine	UBERON:0000160	77.24	gold quality
kidney	UBERON:0002113	76.76	gold quality
colon	UBERON:0001155	76.70	gold quality
heart	UBERON:0000948	75.15	gold quality
small intestine	UBERON:0002108	73.42	gold quality
adult mammalian kidney	UBERON:0000082	72.70	gold quality
muscle of leg	UBERON:0001383	72.48	gold quality
endometrium	UBERON:0001295	72.38	gold quality
Brodmann (1909) area 9	UBERON:0013540	71.55	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	70.21	gold quality
islet of Langerhans	UBERON:0000006	69.89	gold quality
gastrocnemius	UBERON:0001388	69.64	gold quality
cerebral cortex	UBERON:0000956	68.74	gold quality
body of stomach	UBERON:0001161	68.50	gold quality
skin of leg	UBERON:0001511	67.18	gold quality
hypothalamus	UBERON:0001898	66.70	gold quality
placenta	UBERON:0001987	65.82	gold quality
prostate gland	UBERON:0002367	64.54	gold quality
heart left ventricle	UBERON:0002084	64.02	gold quality
Ammon’s horn	UBERON:0001954	62.59	gold quality
right atrium auricular region	UBERON:0006631	61.22	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord83b	ENSMUSG00000077734
rattus_norvegicus	Snord83b	ENSRNOG00000058269

Paralogs (2): SNORD83A (ENSG00000209482), (ENSG00000252945)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.