SNORD89

Summary

SNORD89 (small nucleolar RNA, C/D box 89, HGNC:32750) is a small nucleolar RNA gene on chromosome 2q11.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 692205 — RefSeq curated summary.

At a glance

• Gene type: non-coding (snoRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32750
Approved symbol	SNORD89
Name	small nucleolar RNA, C/D box 89
Location	2q11.2
Locus type	RNA, small nucleolar
Status	Approved
Aliases	HBII-289
Ensembl gene	ENSG00000212283
Ensembl biotype	snoRNA
Entrez	692205
RNAcentral	URS0000633321 — snoRNA, 114 nt, 5 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 snoRNA

ENST00000390981

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000390981 — 1 exons

Exon	Start	End
ENSE00001508765	101272936	101273049

Expression profiles

Bgee: expression breadth ubiquitous, 229 present calls, max score 99.85.

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	99.85	gold quality
granulocyte	CL:0000094	97.51	gold quality
adrenal tissue	UBERON:0018303	96.85	gold quality
monocyte	CL:0000576	96.11	gold quality
leukocyte	CL:0000738	95.96	gold quality
lower esophagus mucosa	UBERON:0035834	95.77	gold quality
right lung	UBERON:0002167	94.95	gold quality
blood	UBERON:0000178	94.64	gold quality
spleen	UBERON:0002106	94.57	gold quality
upper lobe of left lung	UBERON:0008952	93.53	gold quality
upper lobe of lung	UBERON:0008948	92.68	gold quality
endocervix	UBERON:0000458	92.58	gold quality
ectocervix	UBERON:0012249	92.42	gold quality
left uterine tube	UBERON:0001303	92.20	gold quality
omental fat pad	UBERON:0010414	92.16	gold quality
peritoneum	UBERON:0002358	92.11	gold quality
left ovary	UBERON:0002119	92.10	gold quality
calcaneal tendon	UBERON:0003701	92.03	gold quality
esophagus mucosa	UBERON:0002469	91.87	gold quality
adipose tissue of abdominal region	UBERON:0007808	91.14	gold quality
tibial nerve	UBERON:0001323	91.08	gold quality
right ovary	UBERON:0002118	90.97	gold quality
uterine cervix	UBERON:0000002	90.37	gold quality
skin of abdomen	UBERON:0001416	90.35	gold quality
minor salivary gland	UBERON:0001830	90.21	gold quality
lung	UBERON:0002048	89.94	gold quality
right lobe of liver	UBERON:0001114	89.91	gold quality
right coronary artery	UBERON:0001625	89.82	gold quality
descending thoracic aorta	UBERON:0002345	89.73	gold quality
body of pancreas	UBERON:0001150	89.72	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.12

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• SNORD89 can be a novel prognostic biomarker and therapeutic target for ovarian cancer. (PMID:31395064)

Cross-species orthologs

2 orthologs

Organism	Symbol	Gene ID
mus_musculus	Snord89	ENSMUSG00000077704
rattus_norvegicus	Snord89	ENSRNOG00000055019

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.