SOCS3-DT

Summary

SOCS3-DT (SOCS3 divergent transcript, HGNC:52799) is a long non-coding RNA gene on chromosome 17q25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52799
Approved symbol	SOCS3-DT
Name	SOCS3 divergent transcript
Location	17q25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000266970
Ensembl biotype	lncRNA
Entrez	101928674
RNAcentral	URS000075B8AA — lncRNA, 896 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 50 — 50 lncRNA

ENST00000587575, ENST00000592569, ENST00000687996, ENST00000689065, ENST00000691100, ENST00000700856, ENST00000717046, ENST00000794147, ENST00000794148, ENST00000794149, ENST00000794150, ENST00000794151, ENST00000794152, ENST00000794153, ENST00000794154, ENST00000794155, ENST00000794156, ENST00000794157, ENST00000794158, ENST00000794159, ENST00000794160, ENST00000794161, ENST00000794162, ENST00000794163, ENST00000794164, ENST00000794165, ENST00000794166, ENST00000794167, ENST00000794168, ENST00000794169, ENST00000794170, ENST00000794171, ENST00000794172, ENST00000794173, ENST00000794174, ENST00000794175, ENST00000794176, ENST00000794177, ENST00000794178, ENST00000794179, ENST00000794180, ENST00000794181, ENST00000794182, ENST00000794183, ENST00000794184, ENST00000794185, ENST00000794186, ENST00000794187, ENST00000794188, ENST00000794189

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000587575 — 2 exons

Exon	Start	End
ENSE00002739170	78362671	78362751
ENSE00002782648	78364497	78364905

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 76.38.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6913 / max 33.9493, expressed in 342 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
163078	0.4264	204
163077	0.2649	119

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.38	silver quality
colonic epithelium	UBERON:0000397	75.07	gold quality
blood	UBERON:0000178	69.45	gold quality
cortical plate	UBERON:0005343	69.15	gold quality
bone marrow cell	CL:0002092	67.74	silver quality
gall bladder	UBERON:0002110	66.91	gold quality
placenta	UBERON:0001987	65.24	gold quality
upper lobe of left lung	UBERON:0008952	64.65	gold quality
right lobe of liver	UBERON:0001114	64.04	gold quality
omental fat pad	UBERON:0010414	63.08	gold quality
corpus callosum	UBERON:0002336	62.67	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	62.60	gold quality
vermiform appendix	UBERON:0001154	62.57	gold quality
left uterine tube	UBERON:0001303	62.52	gold quality
liver	UBERON:0002107	62.46	gold quality
lymph node	UBERON:0000029	62.37	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.19	gold quality
adult mammalian kidney	UBERON:0000082	61.94	gold quality
lung	UBERON:0002048	61.91	gold quality
kidney	UBERON:0002113	61.57	gold quality
skeletal muscle tissue	UBERON:0001134	61.40	gold quality
apex of heart	UBERON:0002098	61.26	gold quality
ganglionic eminence	UBERON:0004023	61.22	gold quality
metanephros cortex	UBERON:0010533	61.12	gold quality
mucosa of stomach	UBERON:0001199	61.06	gold quality
duodenum	UBERON:0002114	60.87	gold quality
bone marrow	UBERON:0002371	60.75	gold quality
monocyte	CL:0000576	60.59	gold quality
right lobe of thyroid gland	UBERON:0001119	60.16	gold quality
cortex of kidney	UBERON:0001225	59.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.